Abstract：Sanguisorba officinalis L.tastes bitter,sour and astringent,and is slightly cold in nature.It enters the Liver and Large Intestine Meridians,and was first recorded in Shennong Ben Cao Jing(Shennong's Classic of Materia Medica).As a commonly used traditional Chinese medicine in clinical practice,it has the traditional efficacy of cooling blood to stop bleeding,detoxifying and promoting wound healing.This paper systematically reviews the relevant research literatures in recent years,and clarifies that the core chemical constituents of Sanguisorba officinalis L.include saponins(the total content of sanguisorbin Ⅰ/Ⅱ is 1.5 2.1 mg/g),tannins(the content of ellagic acid in carbonized Sanguisorba officinalis L.is up to 34.86 mg/g at maximum),flavonoids,etc.Among the processing technologies,carbonized Sanguisorba officinalis L.has the widest application.Orthogonal tests have confirmed that stir-frying at 250℃ for 14 minutes is the optimal process,which can significantly increase the content of hemostatic active ingredients.Modern pharmacological studies have verified that Sanguisorba officinalis L.and its active components possess various pharmacological effects such as hemostasis,wound repair,intestinal mucosal protection,anti-inflammation,antioxidation,antibacterial activity and immunoregulation.It is widely used in clinical fields including hemorrhagic diseases,skin injuries and inflammatory bowel diseases,and shows unique advantages in the protection against intestinal damage caused by tumor radiotherapy and chemotherapy,as well as the treatment of diabetic foot ulcers.Processing is an important link in the clinical application of Sanguisorba officinalis L.,and different processing methods significantly affect its chemical constituents and pharmacological activities.By comprehensively analyzing the characteristics of chemical constituents,the influence of processing technology,the mechanism of pharmacological effects and the expansion of clinical application of Sanguisorba officinalis L.,this paper points out the existing problems in current research,such as unclear synergistic mechanism of components and insufficient development of non-medicinal parts,so as to provide references for its further research,development and precise clinical application.
王超群, 张贵群, 霍金海. 地榆化学成分、炮制工艺及药理作用研究进展[J]. 哈尔滨医药, 2026, 46(2): 129-133.
Wang Chaoqun, Zhang Guiqun, Huo Jinhai. Research Progress on Chemical Constituents,Processing Technology and Pharmacological Effects of Sanguisorba officinalis L. journal1, 2026, 46(2): 129-133.
2026, Vol. 46 
