CO<sub>2</sub>点阵激光联合超分子水杨酸在治疗痤疮凹陷性瘢痕中的疗效和安全性

doi:10.3969/j.issn.1001-8131.2023.06.015

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (423 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the efficacy and safety of CO₂ dot matrix laser combined with supramolecular salicylic acid in the treatment of acne scar. Methods 116 patients with acne concave scarwere randomly divided into two groups.The control group was treated with CO₂ dot matrix laser alone, and the observation group was treated with CO₂ dot matrix laser combined with supramolecular salicylic acid.The clinical efficacy, skin barrier function index, VAS pain score, ECCA score, and various treatment indexes of the two groups were compared. Results The effective rate of observation group was 89.66%, which was significantly higher than that of control group（65.52%, P< 0.05）; After treatment, the skin water loss, erythema value, melanin value and pH value in the observation group were lower than those in the control group, and the water content in the stratum corneum was higher than that in the control group（P; After treatment, VAS pain score and ECCA score in the observation group were significantly lower than those in the control group（P< 0.05）; The time of scab formation and scab peeling off in the observation group was significantly shorter than that in the control group（P> 0.05）. Conclusion The effect of CO₂ dot matrix laser combined with supramolecular salicylic acid in the treatment of acne scar depression is significant, which can effectively improve the skin barrier function, promote the regression of acne scar depression, accelerate the time of scab formation and scab removal, and the incidence of adverse reactions is low.

Key words： Acne depressed scar CO₂ lattice laser Supramolecular salicylic acid Efficacy Security

Received: 20 December 2022

PACS:

R758.73

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Wang Xiaoyu

Cite this article:

Wang Xiaoyu. Efficacy and Safety of CO₂ Lattice Laser Combined with Supramolecular Salicylic Acid in the Treatment of Acne Concave Scars[J]. journal1, 2023, 43(6): 41-43.

URL:

http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2023.06.015 OR http://www.hrbyybjb.org.cn/EN/Y2023/V43/I6/41

[1] 吴轶西, 曾海燕, 罗文霞, 等.CO₂点阵激光联合果酸治疗痤疮后凹陷性瘢痕的疗效分析[J].皮肤病与性病, 2021, 43(2):304-305.
[2] 肖卫棉, 陈晓琼.超脉冲CO₂点阵激光联用毫针针刺治疗面部凹陷性痤疮瘢痕疗效观察[J].中国美容医学, 2017, 26(11):68-71.
[3] 兰小琼, 易勤, 史修波, 等.超脉冲CO₂点阵激光联合光子嫩肤治疗凹陷性痤疮瘢痕的疗效及影响因素分析[J].现代生物医学进展, 2021, 21(20):3950-3953, 3958.
[4] 郑建辉. 点阵激光联合胶原贴敷料治疗面部痤疮凹陷性瘢痕20例临床观察[J].皮肤病与性病, 2018, 40(2):232-233.
[5] 中国痤疮治疗指南专家组.中国痤疮治疗指南(2019 修订版)[J].临床皮肤科杂志, 2019, 48(9):583-588.
[6] 董玉洁, 李玉叶.1565nm非剥脱点阵激光联合超分子水杨酸治疗面部轻中度痤疮的疗效观察[J].皮肤病与性病, 2021, 43(3):338-339, 370.
[7] 靳艳茹, 杨帆, 刘孝兵, 等.果酸联合胶原蛋白敷料 CO₂点阵激光治疗面部痤疮凹陷性瘢痕的临床观察[J].河北医学, 2019, 25(7):1186-1190.
[8] 李敬, 于霖, 韩凤娴, 等.准长脉宽1064nm Nd:YAG激光联合超分子水杨酸治疗面部轻中度痤疮的临床疗效观察[J].中国中西医结合皮肤性病学杂志, 2020, 19(1):68-71.
[9] 相恒芳. CO₂点阵激光联合胶原蛋白贴敷料治疗面部痤疮凹陷性瘢痕的临床观察[J].社区医学杂志, 2017, 15(16):47-49.
[10] 姜嵩, 张艺琼, 陈媛, 等.超脉冲CO₂点阵激光联合针刺疗法治疗痤疮凹陷性瘢痕的自身对照观察[J].中国皮肤性病学杂志, 2017, 31(8):912-195.
[11] 王怀湘, 李建明, 郑金光, 等.类人胶原蛋白敷料联合超脉冲CO₂点阵激光治疗凹陷性痤疮瘢痕的疗效和安全性[J].武警医学, 2018, 29(7):680-683.
[12] 陈丽芬, 程波, 赵雁, 等.超脉冲CO₂点阵激光联合微针疗法治疗痤疮凹陷性疤痕的效果临床探讨[J].中国医疗美容, 2019, 9(4):36-39.
[13] 鲁亚青, 段亚琼, 范琳婵, 等.超分子水杨酸治疗痤疮的效果及对皮肤屏障的影响[J].中国美容医学, 2020, 29(3):9-11.
[14] 汪勤. 透明质酸敷料联合CO₂点阵激光治疗痤疮凹陷性瘢痕的疗效及对皮肤屏障功能的影响[J].中国激光医学杂志, 2021, 30(4):232-234.
[15] 唐许, 龚成, 刘慧.透明质酸敷料联合超脉冲CO₂点阵激光治疗面部痤疮凹陷性瘢痕疗效分析[J].中国美容医学, 2017, 26(10):88-89, 115.