布托啡诺对男性经尿道膀胱肿瘤切除术后导尿管相关膀胱刺激征的影响

doi:10.3969/j.issn.1001-8131.2024.04.008

Abstract
Figure/Table
References
Related Citation (3)

Download: PDF (538 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective Exploring the effect of butorphanol on catheter-related bladder discomfort（CRBD）after transurethral resection of bladder tumor（TURBT）in males.Methods 68 male patients aged ≥20y and ≤80 years old who underwent TURBT under selective general anesthesia were selected,with ASA grades I to Ⅲ and surgery time ranging from 30 minutes to 120 minutes.Using a random number table generated by online randomization software,patients were divided into two groups：a butorphanol group（Group B）of 34 cases and a control group（Group C）of 34 cases.Group C received anesthesia induction with sufentanil and physiological saline,while Group B received anesthesia induction with sufentanil and butorphanol at a dose of 0.02 mg/kg.Record and compare：①Record the number and degree of CRBD occurrences immediately after extubation（T₀）,1 hour after surgery（T₁）,2 hours after surgery（T₂）,and 6 hours after surgery（T₃）in two groups of patients;②Record the dosage of tramadol and sufentanil for two groups of patients;Record the duration of stay in the Postanesthesia care unit（PACU）after anesthesia for two groups of patients;③Record the sedation levels and incidence of dizziness,nausea,and vomiting in two groups of patients.Results The number and severity of CRBD occurrence in Group B patients at T₀,T₁,T₂,and T₃ were lower than those in Group C,and the difference was statistically significant（P<0.05）.The amount of tramadol used for salvage treatment in Group B patients with moderate to severe CRBD was significantly lower than that in Group C,and the difference was statistically significant（P<0.01）.The duration of stay in PACU in Group B was shorter than that in Group C,and the difference was statistically significant（P<0.05）.There was no statistically significant difference in the amount of sufentanil used for pain relief,the level of sedation within the PACU,and the occurrence of adverse reactions such as dizziness,nausea,and vomiting between the two groups of patients（P>0.05）.Conclusion Butorphanol can significantly reduce the incidence and severity of CRBD after TBRBT surgery,and there are no significant adverse reactions.It can be safely and effectively used to alleviate CRBD.

Key words： Butorphanol Male Transurethral resection of bladder tumor Catheter-related bladder discomfort

Received: 16 April 2024

PACS:

R737.14

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Yin Fengwei
	Chen Mengting
	Xu Chengfei
	Cheng Liang

Cite this article:

Yin Fengwei,Chen Mengting,Xu Chengfei, et al. The Effect of Butorphanol on Urinary Tract Related Bladder Irritation Signs after Male Transurethral Bladder Tumor Resection[J]. journal1, 2024, 44(4): 27-30.

URL:

http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2024.04.008 OR http://www.hrbyybjb.org.cn/EN/Y2024/V44/I4/27

[1] Bala I,Bharti N,Chaubey VK,et al.Efficacy of gabapentin for prevention of postoperative catheter-related bladder discomfort in patients undergoing transurethral resection of bladder tumor[J].Urology,2012,79(4):853-857.
[2] Li S,Song L,Ma Y,et al.Tramadol for the treatment of catheter-related bladder discomfort:a randomized controlled trial[J].BMC Anesthesiol,2018,18(1):194.
[3] Agarwal A,Gupta D,Kumar M,et al.Ketamine for treatment of catheter related bladder discomfort:a prospective,randomized,placebo controlled and double blind study.Br J Anaesth,2006,96(5):587-589.
[4] Zhao Yun Y,Jun Mei X,Rong Z,et al.Dexmedetomidine reduces Catheter-Related Bladder Discomfort:A Prospective,Randomized,Placebo- Controlled,Double-Blind Study[J].P R Health Sci J,2016,35(4):191-196.
[5] Bai Y,Wang X,Li X,et al.Management of Catheter-Related Bladder Discomfort in Patients Who Underwent Elective Surgery[J].J Endourol,2015,29(6):640-649.
[6] Ergenoglu P,Akin S,Yalcin Cok O,et al.Effect of intraoperative paracetamol on catheter-related bladder discomfort:a prospective,randomized,double-blind study[J].Curr Ther Res Clin Exp,2012,73(6):186-194.
[7] Yu D,Chai W,Sun X,et al.Emergence agitation in adults:risk factors in 2,000 patients[J].Can J Anaesth,2010,57(9):843-848.
[8] Lee SJ,Sung TY.Emergence agitation:current knowledge and unresolved questions[J].Korean J Anesthesiol,2020,73(6):471-485.
[9] Pakzad R,Mohammadian-Hafshejani A,Mohammadian M,et al.Incidence and Mortality of Bladder Cancer and their Relationship with Development in Asia[J].Asian Pac J Cancer Prev,2015,16(16):7365-7374.
[10] Burger M,Catto JW,Dalbagni G,et al.Epidemiology and risk factors of urothelial bladder cancer[J].Eur Urol,2013,63(2):234-241.
[11] Du BX,Song ZM,Wang K,et al.Butorphanol prevents morphine-induced pruritus without increasing pain and other side effects:a systematic review of randomized controlled trials[J].Can J Anaesth,2013,60(9):907-917.
[12] Jang EB,Hong SH,Kim KS,et al.Catheter-Related Bladder Discomfort:How Can We Manage It?[J].Int Neurourol J,2020,24(4):324-331.
[13] Viswanathan K,Rosen T,Mulcare MR,et al.Emergency Department Placement and Management of Indwelling Urinary Catheters in Older Adults:Knowledge,Attitudes,and Practice[J].J Emerg Nurs,2015,41(5):414-422.
[14] Meng J,Jiang SJ,Jiang D,et al.Butorphanol attenuates inflammation via targeting NF-kappaB in septic rats with brain injury[J].Eur Rev Med Pharmacol Sci,2019,23(3 Suppl):161-170.
[15] Bonaz B,Riviere PJ,Sinniger V,et al.Fedotozine,a kappa-opioid agonist,prevents spinal and supra-spinal Fos expression induced by a noxious visceral stimulus in the rat[J].Neurogastroenterol Motil,2000,12(2):135-147.