|
|
Research progress on traditional Chinese medicine in the treatment of Lupus nephritis |
Du Jiawen1, Song Liqun2 |
1. Heilongjiang University of Chinese Medicine,Harbin Heilongjiang China 150040; 2. The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin Heilongjiang China 150040 |
|
|
Abstract Lupus nephritis(lupus nephritis,LN)is one of the most common complications of systemic lupus erythematosus(SLE).The traditional view is that the mechanism of this disease is that lymphocytes produce a large number of antibodies against autoantigens and form immune complexes to deposit in different tissues,leading to kidney involvement and showing progressive damage.LN delay is difficult to heal and easy to relapse,and the treatment is mainly using glucocorticoids and immunosuppressants,and the prognosis is poor.In recent years,TCM has conducted a lot of research and exploration in the treatment of LN,and has shown reliable clinical efficacy and safety.The author will summarize and elaborate the research progress in recent years from the aspects of disease name,etiology,treatment method,ancient prescription,Chinese medicine,extract and characteristic treatment of traditional Chinese medicine,in order to provide theoretical reference basis for the clinical work and research of LN.
|
Received: 05 March 2024
|
|
|
|
|
[1] Ameer MA,Chaudhry H,Mushtaq J,et al.An Overview of Systemic Lupus Erythematosus(SLE)Pathogenesis,Classification,and Management.Cureus.2022;14(10):e30330. [2] Kostopoulou M,Fanouriakis A,Bertsias G,Boumpas DT.Annkals of the Rheumatic Diseases collection on lupus nephritis(2019-2022):novel insights and advances in therapy.Ann Rheum Dis.2023;82(6):729-733. [3] Palazzo L,Lindblom J,Mohan C,Parodis I.Current Insights on Biomarkers in Lupus Nephritis:A Systematic Review of the Literature.[J] Clin Med.2022;11(19):5759. [4] Satish S,Deka P,Shetty MS.A clinico-pathological study of lupus nephritis based on the International Society of Nephrology-Renal Pathology Society 2003 classification system.[J] Lab Physicians.2017;9(3):149-155. [5] Bajema IM,Wilhelmus S,Alpers CE,et al.Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis:clarification of definitions,and modified National Institutes of Health activity and chronicity indices.Kidney Int.2018;93(4):789-796. [6] Thompson JC,Mahajan A,Scott DA,Gairy K.The Economic Burden of Lupus Nephritis:A Systematic Literature Review.Rheumatol Ther.2022;9(1):25-47. [7] 李晶,刘红.中西医多联疗法治疗狼疮性肾炎的疗效观察[J].湖北中医杂志,2020,42(03):16-18. [8] 苏亚平,朱建新.系统性红斑狼疮中医命名之我见[J].甘肃中医,2009,22(04):5-6. [9] 方心,邢亚明.系统性红斑狼疮中医命名考辨[J].实用中医内科杂志,2010,24(08):75-76. [10] 姜晨光,汲泓.系统性红斑狼疮中医病名之论[J].风湿病与关节炎,2022,11(04):59-61. [11] 柴霞尔,俞东容.狼疮性肾炎的中医病名及分型辨治研究综述[J].江西中医药大学学报,2014,26(05):94-96. [12] 白牧鑫,江燕,孙伟.余承惠治疗狼疮性肾炎经验[J].辽宁中医杂志,2020,47(05):56-58 [13] 邓滢滢,程德金,曾桂桃,等.汤水福辨治岭南狼疮性肾炎经验[J].广州中医药大学学报,2021,38(10):2254-2259. [14] 周道成,赵恒侠,李惠林,等.王孟庸从标本论治狼疮性肾炎临床经验[J].中国中医药信息杂志,2018,25(01):105-107. [15] 韩宜臻,王耀献,陶嘉茵,等.从伏热论治狼疮性肾炎经验[J].中华中医药杂志,2022,37(11):6554-6557. [16] 辛雪艳,杨丛旭.许家松教授治疗狼疮性肾炎经验撷英[J].世界中西医结合杂志,2021,16(12):2213-2216. [17] 张丹君,鲁盈.鲁盈教授祛风除湿法治疗狼疮性肾炎的经验探析[J].浙江中医药大学学报,2021,45(02):171-174. [18] 王慧娟,梁晓平,宋辉,等.梁晓平从本虚标实分型辨治狼疮性肾炎经验[J].中医药临床杂志,2020,32(03):436-439. [19] 李述捷,陈晓玲,郑关毅,等.阮诗玮辨治狼疮性肾炎经验[J].中医药通报,2021,20(02):15-17+72. [20] 薛山,王亿平,王东.王亿平辨治狼疮性肾炎经验[J].中医药通报,2023,22(03):6-8. [21] 於丹燕,应旭旻.中医药治疗狼疮性肾炎研究进展[J].浙江中西医结合杂志,2021,31(11):1078-1080. [22] 王晴晴,谌曦.基于“正邪理论”探讨谌曦论治狼疮性肾炎伴血小板减少临床经验[J].中医药临床杂志,2023,35(01):40-43. [23] 李仕仪,林燕.曹式丽治疗狼疮性肾炎经验[J].河南中医,2022,42(07):1026-1031. [24] 张丹丹,温成平.运用水血并治法治疗狼疮性肾炎体会[J].中医杂志,2017,58(05):427-429. [25] 闫蒙蒙,任永朋,邢海燕等.王自敏教授辨治狼疮性肾炎的经验及医案举隅[J].浙江中医药大学学报,2020,44(09):881-884. [26] 王超,杨翠,汤水福.汤水福辨治狼疮性肾炎的临床经验[J].广州中医药大学学报,2017,34(04):592-594. [27] 李春深编著.验方新编[M].天津:天津科学技术出版社,2019.01. [28] 宋庆良,伍劲华,马春成.名中医伍劲华治疗狼疮性肾炎经验总结[J].亚太传统医药,2023,19(06):134-137. [29] 郑小丽,薛永亮,李小全,等.四妙勇安汤加减联合免疫抑制剂及醋酸泼尼松片对轻中度活动期狼疮性肾炎患者SLEDAI积分及ESR、C3水平的影响[J].中医药临床杂志,2020,32(01):145-148. [30] 刘飞,张红霞,席春生,等.利妥昔单抗联合真武汤治疗狼疮性肾炎临床观察[J].新中医,2018,50(09):92-94. [31] 黄爱梅,宋燕,殷卫东,等.参芪地黄汤联合环磷酰胺对气阴两虚型狼疮性肾炎血清趋化因子配体16、CXCL10、CXCL11以及CXCL9影响探究[J].中华中医药学刊,2021,39(12):221-224. [32] 龚晓红,李松伟,李桓,等.青蒿鳖甲汤化裁治疗阴虚型系统性红斑狼疮增效减毒的Meta分析[J].风湿病与关节炎,2020,9(09):33-38+42. [33] 尹晓华,马秀琴,李莉,等.青蒿鳖甲汤加减对阴虚内热证狼疮性肾炎的疗效[J].西北药学杂志,2023,38(02):161-165. [34] 管鑫,杨雨竹,刘伟伟,等.黄芪桂枝五物汤在肾脏病中的临床应用[J].中国中西医结合肾病杂志,2019,20(12):1127-1128. [35] 谢帆,董飞侠.董飞侠运用经方升麻鳖甲汤治疗狼疮性肾炎经验[J].中国中医基础医学杂志,2019,25(10):1453-1455. [36] 王尚飞. 益气滋阴祛瘀方联合注射用环磷酰胺对阴虚内热、瘀血痹阻型狼疮性肾炎患者的临床疗效[J].实用中西医结合临床,2022,22(06):64-66. [37] 边彩月,范文强,高晓,等.益肾祛瘀化湿汤对狼疮性肾炎患者肾功能和NGAL、HMGB1、sTM、IGBP1水平的影响[J].中医药信息,2022,39(05):60-64. [38] 张伊锐,刘炎,李慧丽,等.刘绍武治疗狼疮性肾炎经验方消斑解毒汤的组方思路探析[J].时珍国医国药,2021,32(12):3025-3026. [39] 李坤伦,黄集彬,蒋颖钰,等.自拟狼疮护肾方治疗狼疮性肾炎作用机制探讨[J].中国中医急症,2020,29(01):127-129. [40] 梁谋,钟建瑜,张震,等.肾安汤联合激素及免疫抑制剂治疗狼疮性肾炎30例[J].湖南中医杂志,2019,35(08):7-10. [41] 王洁,李源,姚硕,等.槐杞黄颗粒辅助治疗狼疮性肾炎的疗效及对患者血清铁蛋白的影响[J].中国医院用药评价与分析,2022,22(09):1060-1063. [42] 赵琳娜,李洪艳,张威,等.昆仙胶囊联合来氟米特治疗狼疮性肾炎临床疗效的回顾性研究[J].现代生物医学进展,2022,22(08):1489-1493. [43] 农聪,赵晓月,黄文,等.黄葵胶囊联合硫唑嘌呤治疗狼疮性肾炎的临床研究[J].现代药物与临床,2022,37(04):809-812. [44] 郭佳音,梁素忍,常洁.金水宝胶囊联合泼尼松治疗狼疮性肾炎的临床研究[J].现代药物与临床,2022,37(03):592-596. [45] 吴国伟,夏常玲.金匮肾气丸对狼疮性肾炎患者的临床疗效评价[J].宁夏医学杂志,2021,43(04):375-378. [46] 阿古达木,陈薇薇,苏晓.中医药辨治狼疮性肾炎研究进展[J].西部中医药,2021,34(01):130-133. [47] Yuan K,Li X,Lu Q,et al.ApplicationApplication and Mechanisms of Triptolide in the Treatment of Inflammatory Diseases-A Review.Front Pharmacol.2019;10:1469.Published 2019 Dec 6. [48] 段然,吴沅皞,刘维.雷公藤甲素减轻MRL/lpr狼疮小鼠肾损伤的作用机制研究[J].中国现代医学杂志,2021,31(02):7-12. [49] Wang W,Cao L,Wang X,Fan Y.Radix Paeoniae Rubra Ameliorates Lupus Nephritis in Lupus-Like Symptoms of Mrl Mice by Reducing Intercellular Cell Adhesion Molecule-1,Vascular Cell Adhesion Molecule-1,and Platelet Endothelial Cell Adhesion Molecule-1 Expression.Comb Chem High Throughput Screen.2020;23(7):675-683. [50] 张明昊,王珍,高一盈,等.白芍总苷对雷公藤多苷治疗湿疹的增效减毒作用及机制[J].中国药房,2023,34(04):444-449+456. [51] Xu W,Chen Z,Shen X,et al.Reno-Protective Effect of Realgar Nanoparticles on Lupus Nephritis of MRL/Lpr Mice through STAT1.Iran [J] Immunol.2019;16(2):170-181. [52] 李蔷,毋静,黄瑜亮,等.豨莶草治疗MRL/lpr小鼠狼疮性肾炎疗效初观察[J].现代中药研究与实践,2019,33(04):12-16. [53] Jin Q,Liu T,Chen D,,et al.Therapeutic potential of artemisinin.Therapeutic potential of artemisinin and its derivatives in managing kidney diseases.Front Pharmacol.2023 Feb 15;14:1097206. [54] 卢岚. 冬虫夏草和青蒿素抑制狼疮性肾炎复发的研究[J].中国中西医结合杂志,2002(03):169-171. [55] Liu L,Zhang L,Li M.Application of herbal traditional Chinese medicine in the treatment of lupus nephritis.Front Pharmacol.2022 Nov 24;13:981063. |
[1] |
. [J]. journal1, 2023, 43(1): 132-134. |
[2] |
. [J]. journal1, 2022, 42(5): 135-137. |
|
|
|
|