七氟烷复合丙泊酚瑞芬太尼静吸复合麻醉模式对腹腔镜胆囊切除术患者的影响

doi:10.3969/j.issn.1001-8131.2025.01.005

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Abstract Objective To analyze effects of combined intravenous and inhalation anesthesia on patients undergoing laparoscopic cholecystectomy. Methods 150 consecutive patients who underwent laparoscopic cholecystectomy were randomly assigned to either the observation group（n=75）or the control group（n=75）using a block randomization method.The control group was given propofol combined with remifentanil intravenous anesthesia,and the observation group was given sevoflurane combined with propofol and remifentanil intravenous inhalation combined anesthesia.The postoperative recovery,basic vital signs and stress were observed in the two groups. Results In the observation group,all recovery times were significantly shorter than those in the control group（P<0.05）.No significant differences in SpO₂ levels were observed between the two groups at different time points（P>0.05）.Prior to anesthesia,there were no significant differences in systolic blood pressure（SBP）,diastolic blood pressure（DBP）,and heart rate（HR）between the two groups（P>0.05）.Post-anesthesia,intraoperatively,and postoperatively,the observation group exhibited significantly lower SBP,DBP,and HR levels compared to the control group（P<0.05）.Preoperatively,no significant differences were found in blood glucose,norepinephrine,epinephrine,and cortisol levels between the two groups（P>0.05）.Postoperatively,the observation group showed a decrease in blood glucose,norepinephrine,epinephrine,and cortisol levels,while the control group exhibited an increase;levels in the observation group were significantly lower than those in the control group（P<0.05）. Conclusion sevoflurane combined with propofol-remifentanil intravenous inhalation combined anesthesia is effective in laparoscopic cholecystectomy,which can effectively shorten the postoperative recovery time,maintain intraoperative hemodynamic stability,and inhibit stress response.

Key words： sevoflurane Propofol remifentanil combined intravenous and inhalational anesthesia laparoscopic cholecystectomy

Received: 12 February 2025

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R614.2

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	Articles by authors
	Wang Lijuan
	Cao Jie
	Jia Haipeng
	Cui Yujun

Cite this article:

Wang Lijuan,Cao Jie,Jia Haipeng, et al. Effect of Sevoflurane Combined with Propofol Remifentanil Intravenous Combined Anesthesia Mode in Patients undergoing Laparoscopic Cholecystectomy[J]. journal1, 2025, 45(1): 14-17.

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http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2025.01.005 OR http://www.hrbyybjb.org.cn/EN/Y2025/V45/I1/14

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