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| Effect of Yangyin Yifei Decoction on Serum NO,VEGF Levels and KPS Scores in Patients With Non-Small Cell Lung Cancer |
| Shen Qixin, Zhou Dongdong, Liu Jie |
| Department of Oncology,Zhumadian Traditional Chinese Medicine Hospital,Zhumadian 463000,Henan |
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Abstract Objective To investigate the effect of Yangyin Yifei Decoction on serum nitric oxide（NO）,vascular endothelial growth factor（VEGF）levels and KPS in patients with non-small cell lung cancer. Methods The clinical data of 60 patients with non-small cell carcinoma treated were retrospectively analyzed.31 patients treated with GP chemotherapy combined with Yangyin Yifei Decoction were included in the observation group.29 patients treated with GP chemotherapy were included in the control group.3 weeks was a course of treatment,and both groups were treated continuously for 2 courses.The KPS score,serum NO and VEGF levels,and the recurrence rate within 1 year were compared between the two groups. Results After 6 weeks of treatment,the KPS score and NO level of the observation group were higher than that of the control group,the VEGF level was lower than that of the control group,and the recurrence rate of the observation group within 1 year was lower than that of the control group.The difference was statistically significant（P<0.05）. Conclusion Yangyin Yifei Decoction can improve serum NO level and reduce blood VEGF concentration in patients with non-small cell lung cancer,and it has a significant effect in promoting patient recovery and improving prognosis.
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Received: 12 September 2020
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2021, Vol. 41 
