|
|
|
| Diagnostic Significance of Multi-slice Spiral CT Angiography Combined with Serum Lipoprotein-a Testing for Preoperative Classification of Acute Aortic Dissection |
| Wang Gaojun, Yang Hongwei, Wang Dateng, Yang Ming |
| Department of Cardiovascular Surgery,First Affiliated Hospital of Nanyang Medical College,Nanyang,Henan 473000,China |
|
|
|
|
Abstract Objective To analyse the diagnostic significance of multi-slice spiral computed tomography angiography(CTA)combined with serum lipoprotein-a testing for preoperative classification of acute aortic dissection(AAD). Methods A retrosp-ective analysis was conducted on the clinical data of 92 AAD patients admitted to the Department of Cardiovascular Surgery,First Affiliated Hospital of Nanyang Medical College between January 2022 and December 2024.All patients underwent preoperative CTA and serum lipoprotein-a testing.Serum lipoprotein-a levels were compared across different Stanford classi-fications.Diagnostic outcomes and efficacy(sensitivity,specificity,accuracy)were evaluated for CTA,serum lipoprotein-a alone,and their combined use in classifying AAD. Results Surgical confirmation revealed 32(34.78%)Stanford Type A and 60(65.22%)Stanford Type B cases among the 92 patients.Serum lipoprotein-a levels were significantly higher in Stanford type A patients than in Stanford type B patients(P<0.05).No significant differences were observed in specificity or accuracy between CTA,combined CTA-lipoprotein-a diagnosis,and either modality alone(P>0.05).The diagnostic sensitivity of combined CTA and serum lipopro-tein-a was 96.88%(31/32),surpassing that of CTA alone(75.00%,24/32)and serum lipoprotein-a alone(59.38%,19/32)(P<0.05). Conclusion Combined CTA and serum lipoprotein-a testing effectively enhances the sensitivity of preoperative Stanford classification for AAD,providing reliable reference for early accurate classification and treatment planning in clinical practice.
|
|
Received: 03 February 2026
|
|
|
|
|
|
[1] 崔荣敏,龚琪,王哲,等.术前血清sCD163、sTWEAK水平与StanfordA型主动脉夹层动脉瘤患者预后的关系[J].疑难病杂志,2022,21(9):896-900,906. [2] 李海波,刘志妍,王娟,等.主动脉夹层患者术前CTA扫描参数与术后主动脉重构的相关性分析[J].影像研究与医学应用,2025,9(19):76-78. [3] 王伟光,薛超,赵宏亮,等.头颈部联合胸腹主动脉CTA扫描用于急性A型主动脉夹层手术指导:单中心的220例经验[J].中华胸心血管外科杂志,2025,41(11):664-670. [4] 杨宜恒.脂蛋白(a)与主动脉夹层的相关性分析[D].南昌大学医学部,2023. [5] 赵晓培. CTA结合MRA在DeBakeyⅠ-Ⅲ型主动脉夹层诊断价值上的研究[J].辽宁医学杂志,2023,37(6):23-26. [6] 乔健,葛阳阳,曹龙,等.基于CTA影像学的StanfordB型主动脉夹层破口最大直径精准测量研究[J].解放军医学院学报,2025,46(6):583-589,622. [7] 张云燕. 血清脂蛋白a水平与急性主动脉夹层相关性研究[D].温州医科大学,2019. [8] 牛永胜,聂帅,黄福华,等.脂蛋白相关磷脂酶A2早期预测急性A型主动脉夹层预后的前瞻性队列研究[J].中国胸心血管外科临床杂志,2020,27(9):1031-1036. [9] 张石龙. NLR、LP(a)在急性主动脉夹层早期诊断中的应用价值[D].海南医科大学,2024. [10] 刘建华,蒋伟,闫小清,等.IMA、LP-a与StanfordA型主动脉夹层动脉瘤术预后的关系[J].分子诊断与治疗杂志,2022,14(8):1389-1393. [11] 陈德峰,王爱英,贺宝臣,等.CTA、TTE结合D-D在DeBakeyⅠ-Ⅲ型主动脉夹层诊断中的应用[J].中国实验诊断学,2025,29(9):1069-1073. [12] 张俊伟,马俊贤,王晓冬,等.CTA、超声联合D-二聚体在StanfordA型主动脉夹层及其分型诊断中的应用[J].中国CT和MRI杂志,2024,22(12):77-79,83. [13] 范璐,孙玮,李姝琪,等.主动脉夹层患者术前主动脉CTA扫描参数与术后主动脉重构的关系研究[J].中国循证心血管医学杂志,2023,15(10):1199-1202. [14] 施燕,黄政.胸腹血管CTA在胸腹主动脉夹层诊断价值中的研究[J].医药前沿,2017,7(26):102. |
| [1] |
Li Shiyi, Chen Chunbing, Wang Rentang, Wu Yu, Wang Ying. Value Analysis of MSCT Reconstruction Combined with CT Angiography in the Diagnosis of Thoracoabdominal Aortic Dissection[J]. journal1, 2026, 46(1): 27-30. |
| [2] |
. [J]. journal1, 2026, 46(1): 79-81. |
| [3] |
. [J]. journal1, 2025, 45(6): 91-93. |
| [4] |
. [J]. journal1, 2025, 45(6): 89-90. |
| [5] |
. [J]. journal1, 2025, 45(6): 94-96. |
| [6] |
. [J]. journal1, 2025, 45(5): 127-129. |
|
|
|
|