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| Clinical Comparison of 3D-ICBT and IC-ISBT for Locally Advanced Cervical Cancer |
| Zhang Rui, Jiang Qingfang, Feng Gaoqing, Zhang Minjie, Zhang Yuanhang |
| Kaifeng Cancer Hospital,Radiotherapy Ward one,Kaifeng 475003,Henan,China |
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Abstract Objective To compare the application of 3D-ICBT and IC-ISBT in the treatment of locally advanced cervical cancer. Methods 60 patients with locally advanced cervical cancer were divided into the IC-ISBT group(34 cases)and the 3D-ICBT group(26 cases)based on the treatment regimen. Results The short-term efficacy,irradiation dose of clinical target volume and organs at risk,adverse reactions were compared between the two groups(P<0.05).The D90%(EQD2)of high-risk clinical target volume in the IC-ISBT group was significantly higher than that in the 3D-ICBT group(P<0.05).There was no difference in the D90%(EQD2)of intermediate-risk clinical target volume between the two groups(P>0.05).The D1cm3(EQD2)and D2cm3(EQD2)of rectum and bladder in the IC-ISBT group were significantly lower than those in the 3D-ICBT group(P<0.05).There was no difference in the D1cm3(EQD2)and D2cm3(EQD2)of sigmoid colon and small intestine between the two groups(P>0.05).Compared with the 3D-ICBT group,the incidence of radiation cystitis and radiation enteritis in the IC-ISBT group were significantly reduced(P<0.05). Conclusion Compared with 3D-ICBT,IC-ISBT can more significantly increase the radiation dose to high-risk clinical target volume in patients with locally advanced cervical cancer,reduce the irradiation dose to organs at risk,and thereby improve the short-term ORR while reducing the risk of local adverse reactions caused by radiotherapy.
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Received: 04 February 2026
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[1] 樊涛,徐瑞凤,侯士于.容积旋转调强放疗联合三维后装放疗治疗老年宫颈癌的近期疗效分析[J].中国妇产科临床杂志,2025,26(05):396-398.
[2] Chargari C,Peignaux K,Escande A,et al.Radiotherapy of cervical cancer[J].Cancer Radiother,2022,26(1-2):298-308.
[3] 祁鹏,牛书雷,王静,等.三维后装精准放疗联合体外调强外照射治疗宫颈癌的疗效及安全性[J].西部医学,2024,36(9):1341-1345.
[4] Zhao T,Chen Y,Qiu B,et al.Evaluating the accumulated dose distribution of organs at risk in combined radiotherapy for cervical carcinoma based on deformable image registration[J].Brachytherapy,2023,22(2):174-180.
[5] 孙微波,吴晓翠,孙明霞,等.超声引导下的腔内联合组织间插植放疗与三维腔内后装治疗在IIB期宫颈癌治疗中的应用[J].医药论坛杂志,2022,43(02):76-80.
[6] 邹育林,朱思瑾,谭嗣盟.腔内联合组织间插植放疗与三维后装腔内放疗治疗局部晚期宫颈癌的疗效及剂量学参数比较[J].现代肿瘤医学,2024,32(01):115-120.
[7] 梁黎,蒋聪,刘秦嵩,等.三维宫旁插植后装放疗与体外调强放疗对宫颈癌患者膀胱、乙状结肠及直肠受照剂量的影响[J].川北医学院学报,2022,37(03):382-386. |
| [1] |
Zinati Nuertai, Rou Qian, Zhang Meng, Ming Jie, Liu Ying. ALDH1A1 and miR-140: Potential Therapeutic Targets and Strategies for Cervical Cancer[J]. journal1, 2025, 45(3): 1-6. |
| [2] |
. [J]. journal1, 2024, 44(3): 96-98. |
| [3] |
. [J]. journal1, 2024, 44(1): 140-141. |
| [4] |
Wang Feigang, Lu Junpeng, Miao Hongyan. Comparative Analysis of Consistency between Abnormal Results of Thin-layer Liquid-based Cytology and Histopathological Diagnosis in 89 cases[J]. journal1, 2023, 43(6): 44-46. |
| [5] |
. [J]. journal1, 2023, 43(6): 73-75. |
| [6] |
. [J]. journal1, 2023, 43(4): 105-107. |
|
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2026, Vol. 46 
