哮喘和慢阻肺及哮喘-慢阻肺重叠综合征患者生物学标志物的比较分析

doi:10.3969/j.issn.1001-8131.2026.02.005

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (608 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To compare biomarkers in asthma,COPD,and asthma-COPD overlap(ACO). Methods 50 patients per group(asthma,COPD,ACO,and healthy controls)were included.Inflammatory,protease-related,and fibrotic biomarkers were analyzed.Correlation analysis assessed biomarker-disease associations. Results Eosinophilic markers(FeNO, IL-5)were highest in asthma,neutrophil/protease markers(MMP-9, NE)in COPD,and TGF-β in ACO.FeNO correlated strongly with asthma,MMP-9 with COPD,and TGF-β most strongly with ACO. Conclusion Asthma shows eosinophilic inflammation,COPD exhibits neutrophilic inflammation and oxidative stress,while ACO combines features of both with a distinct pro-fibrotic profile.

Key words： Asthma COPD Asthma-COPD Overlap Biomarkers

Received: 15 February 2026

PACS:

R256.12

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Yao Zhihui
	Liu Xingdong
	Xie Junying

Cite this article:

Yao Zhihui,Liu Xingdong,Xie Junying. Comparison of Biomarkers in Asthma COPD and Asthma-COPD Overlap[J]. journal1, 2026, 46(2): 19-22.

URL:

http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2026.02.005 OR http://www.hrbyybjb.org.cn/EN/Y2026/V46/I2/19

[1]	. [J]. journal1, 2026, 46(4): 48-51.
[2]	. [J]. journal1, 2026, 46(4): 133-135.
[3]	. [J]. journal1, 2026, 46(2): 103-106.
[4]	Yang Zhilu, Sha ZhengKai, Zhang Xiangjie, Zhang Pan, Liu Xiaoxiao. Analysis of Risk Factors for Lung Cancer in Chronic Obstructive Pulmonary Disease with Emphysema Type[J]. journal1, 2026, 46(1): 8-12.
[5]	. [J]. journal1, 2025, 45(5): 104-106.
[6]	. [J]. journal1, 2025, 45(2): 75-77.