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| Expression of Trap 1 and EGF in Esophageal Carcinoma and Their Relationship With Clinicopathology |
| Zhang Cuifen, Wang Yongfeng, Zhang Hongge |
| Department of Pathology, Anyang People's Hospital, Anyang 455000, China |
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Abstract Objective To study the expression levels of TRAP1 and EGF in esophageal cancer,and to analyze the correlation between these two indexes and Clinicopathology. Methods 48 patients with esophageal cancer treated were included in the observation group;At the same time,48 healthy people were included as the control group.The levels of TRAP1 and EGF in the tissues of patients were detected by immunohistochemical method,and the correlation between these two indexes and clinical cases was analyzed. Results The positive rates of TRAP1 and EGF in the observation group were higher than those in the control group.There was a positive correlation between these two indexes and TNM stage,location,lymphatic metastasis and degree of differentiation in the observation group（P<0.05）. Conclusion The levels of TRAP1 and EGF in patients with esophageal cancer are significantly different from those in normal population,which can be used as an important index for the diagnosis of esophageal cancer.At the same time,the close correlation between these two indexes and Clinicopathology also provides a new basis for more scientific and reasonable treatment of esophageal cancer.
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Received: 27 August 2021
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[1] 薛松涛. PADI4在食管鳞癌中的表达水平及其生物学功能的研究[D].福建:福建医科大学,2019.
[2] 曹小琴. 非高发区食管癌筛查人群食管病理分布[J].中国肿瘤,2019,28(10):731-737.
[3] 田慧玲,田红艳.食管癌病理特点及治疗预后的影响因素[J].全科口腔医学电子杂志,2019,21(2):3-6
[4] 澹会芳,赵学科,高社干,等.食管癌核心家系患者临床病理特征及术后预后分析[J].郑州大学学报(医学版),2019,233(2):21-25.
[5] 周胜利,陈伟,柏根基,等.双能量CT及DWI食管癌病理分级对照[J].放射学实践,2020,35(6):746-749.
[6] 王永凤,景诗学.70例食管癌切除标本临床病理分析[J].健康养生,2019,9(15):159.
[7] 赵红霞,江玲娜,涂开峰,等.食道癌与相关基因的研究进展[J].黄冈职业技术学院学报,2019,21(2):89-91.
[8] 刘晓波,高子夜,金曙,等.食管癌患者与健康对照者的食管菌群差异分析[J].中华消化杂志,2021,41(3):165-170.
[9] 孙静,王铸.ADC值对食管癌T分期及病理分级的诊断价值[J].磁共振成像,2020,11(7):531-534. |
| [1] |
. [J]. journal1, 2021, 41(6): 114-115. |
| [2] |
. [J]. journal1, 2021, 41(3): 69-70. |
| [3] |
. [J]. journal1, 2021, 41(3): 95-96. |
| [4] |
Li Shuaifeng, Yao Huajian, Liu Zhigang. Application Value of Tubular Gastroesophageal Anastomosis in Radical Resection of Esophageal Cancer[J]. journal1, 2021, 41(1): 10-11. |
| [5] |
. [J]. journal1, 2021, 41(1): 78-79. |
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2022, Vol. 42 
