中医药治疗狼疮性肾炎的研究进展
杜家文1 , 宋立群2
1.黑龙江中医药大学,黑龙江 哈尔滨 150040;
Research progress on traditional Chinese medicine in the treatment of Lupus nephritis
Du Jiawen1 , Song Liqun2
1. Heilongjiang University of Chinese Medicine,Harbin Heilongjiang China 150040;
摘要 狼疮性肾炎（lupus nephritis,LN）是系统性红斑狼疮（systemic lupus erythematosus,SLE）最常见的并发症之一。传统观点认为本病的发生机制为淋巴细胞针对自身抗原产生了大量抗体,并形成免疫复合物沉积于不同组织,导致肾脏的受累,并呈现出进行性损害。LN迁延难愈,容易复发,治疗以应用糖皮质激素和免疫抑制剂为主,预后欠佳。近年来,中医药在治疗LN方面进行了大量研究与探索,并且显示出了可靠的临床疗效和安全性。笔者将从病名、病因病机、论治方法、古方、自拟方、中成药、中药单体及提取物和中医特色治疗等方面对近年来的研究进展进行总结和阐述,以求为LN的临床工作和研究提供理论参考依据。
关键词 ：
狼疮性肾炎 ,
中医药 ,
研究进展
Abstract ：Lupus nephritis（lupus nephritis,LN）is one of the most common complications of systemic lupus erythematosus（SLE）.The traditional view is that the mechanism of this disease is that lymphocytes produce a large number of antibodies against autoantigens and form immune complexes to deposit in different tissues,leading to kidney involvement and showing progressive damage.LN delay is difficult to heal and easy to relapse,and the treatment is mainly using glucocorticoids and immunosuppressants,and the prognosis is poor.In recent years,TCM has conducted a lot of research and exploration in the treatment of LN,and has shown reliable clinical efficacy and safety.The author will summarize and elaborate the research progress in recent years from the aspects of disease name,etiology,treatment method,ancient prescription,Chinese medicine,extract and characteristic treatment of traditional Chinese medicine,in order to provide theoretical reference basis for the clinical work and research of LN.
Key words ：
lupus nephritis
traditional Chinese medicine
research progress
收稿日期: 2024-03-05
基金资助: 宋立群全国名老中医药专家传承工作室建设项目（国中医药人教函[2022]75号）
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2024, Vol. 44 
