Abstract：Objective To investigate the efficacy of stellate ganglion block(Stellate Ganglion Block,SGB)combined with cognitive behavioral therapy for insomnia(Cognitive Behavioral Therapy for Insomnia,CBT-I)in the treatment of intractable insomnia. Methods 80 patients were selected as the study subjects.These patients were randomly assigned to two groups,each containing 40 patients.Patients in the control group received SGB therapy,whereas those in the observation group received a combination of SGB therapy with CBT-I therapy.Treatment response rate,Pittsburgh Sleep Quality Scale(pittsburgh sleep quality index,PSQI)scores,and psychological status were compared. Results The total effective rate of treatment in the observation group was 92.50%,which was higher than that of the control group at 72.50%(χ2=5.541,P=0.019).Before treatment,there was no significant difference in PSQI scores between the two groups(P>0.05).At 2,4,and 8 weeks after treatment,PSQI scores in both groups decreased,and those in the observation group were significantly lower than those in the control group(P<0.05).After treatment,SAS and SDS scores in both groups showed a downward trend,and those in the observation group were lower than those in the control group(P<0.05).The dropout rate in the observation group was 2.50%,which was lower than that of the control group at 17.50%(χ2=5.000,P=0.025). Conclusion SGB combined with CBT-I has significant clinical effects in the treatment of intractable insomnia,which can effectively improve the sleep quality,reduce anxiety and depression,and have mild adverse reactions and good patient compliance.It is a comprehensive treatment method worthy of promotion.
李一, 高鹏涛. 基于星状神经节阻滞联合CBT-I治疗顽固性失眠的疗效观察[J]. 哈尔滨医药, 2025, 45(3): 7-10.
Li Yi, Gao Pengtao. Based on the Efficacy of Stellate Ganglion Block Combined with CBT-I in Intractable Insomnia. journal1, 2025, 45(3): 7-10.
[1] Kunz D,Dauvilliers Y,Benes H,et al.Long-Term Safety and Tolerability of Daridorexant in Patients with Insomnia Disorder[J].CNS Drugs,2023,37(1):93-106. [2] McElroy H,O'Leary B,Adena M,et al.Comparative efficacy of lemborexant and other insomnia treatments:a network meta-analysis[J].J Manag Care Spec Pharm,2021,27(9):1296-1308. [3] Liu Y,Zhang L,Sun Y,et al.Efficacy and safety of stellate ganglion block with different volumes of ropivacaine to improve sleep quality in patients with insomnia:a comparative study[J].Eur Rev Med Pharmacol Sci,2023,27(21):10233-10239. [4] Alimoradi Z,Jafari E,Brostrm A,et al.Effects of cognitive behavioral therapy for insomnia(CBT-I)on quality of life: A systematic review and meta-analysis[J].Sleep Med Rev,2022,64:101646. [5] 杨甫德,陈彦方.中国失眠防治指南[S].北京:人民卫生出版社,2012:24-26. [6] 国家中医药管理局.中医病证诊断疗效标准[M].北京:中国医药科技出版社,2012:93-94. [7] 国家卫生健康委员会官网,中国新闻网,《人民日报》编辑部,等.报告称居民日平均睡眠不足7小时[J].中医健康养生,2024,10(4):3. [8] 刘琼,关双,陈亚飞,等.中西医治疗顽固性失眠的研究进展[J].中国中医基础医学杂志,2021,27(10):1670-1674. [9] 谭天辉,曹雪梅.基于形神兼顾的动静调神法治疗顽固性失眠思路探讨[J].新中医,2024,56(11):130-134. [10] 郭秀珍. 颊针联合星状神经节阻滞治疗顽固性失眠的临床效果研究[J].科技与健康,2024,3(9):61-64. [11] 杨淑珍,高胜奎,白东梅,等.甘麦大枣汤联合失眠认知行为疗法治疗抑郁共病失眠的疗效观察[J].河西学院学报,2024,40(2):1-7. [12] 胡俊,张静.乌灵胶囊联合失眠认知行为治疗(CBT-Ⅰ)、药物治疗失眠伴焦虑状态的临床研究[J].实用中医内科杂志,2022,36(7):100-102. [13] 孟令娜,王娜娜,韩晓嫣,等.失眠认知行为疗法对慢性失眠症患者焦虑及睡眠的影响[J].临床心身疾病杂志,2023,29(6):96-99. [14] 苏秋菊. 低频电针联合认知行为疗法干预失眠短期效果回顾性分析[J].中国医药科学,2024,14(09):122-126. [15] 张宇,高燕鲁.失眠障碍的认知行为疗法研究进展[J].神经疾病与精神卫生,2024,24(04):277-281. [16] 谢玉艳,孙菊光.失眠认知行为疗法结合中药辨证施治对失眠障碍疗效分析[J].世界睡眠医学杂志,2023,10(9):2053-2057. [17] 梁巧玲,徐国洪,刘紫珊,等.短程团体失眠认知行为疗法在慢性失眠患者护理中的应用效果[J].当代护士(上旬刊),2023,30(1):86-91. [18] 卫琰,刘庆,朱震宏,等.乌灵胶囊联合星状神经节阻滞治疗焦虑性失眠疗效观察[J].海南医学,2022,33(6):732-735.
2025, Vol. 45 
