Abstract：Objective To analyze the pathogenic bacteria and risk factors of infection in patients with purulent keratitis.Methods A total of 115 patients with purulent keratitis were selected,their clinical data were collected,pathogenic examinations,drug resistance analysis,and risk factors for infection were analyzed.Results The main pathogenic bacteria in 115 patients with purulent keratitis were gram-positive bacteria.Among the main gram-positive bacteria,Staphylococcus epidermidis was highly resistant to ampicillin,piperacillin and erythromycin,and streptococcus hemolyticus was resistant to ampicillin.Pseudomonas aeruginosa,which is the main gram-negative bacteria,is highly resistant to ampicillin and erythromycin.Multi-factor analysis found that the history of eye surgery,wearing contact lenses,Ocular surface disease,use of antibacterial drugs,eye trauma or corneal foreign body,TC≤4.31mmol/L,WBC>6.67×109/L,ALB≤39.21g/L,Hb≤134.87g/L,CRP≥1.18mg/L All are risk factors for infection in patients with purulent keratitis（P<0.05）.Conclusion History of eye surgery,wearing contact lenses,ocular surface diseases,use of antibiotics,ocular trauma or corneal foreign bodies are risk factors for patients with purulent keratitis;the main pathogenic bacteria in patients with purulent keratitis are gram-positive bacteria,And the bacteria have the problem of multi-drug resistance,the clinic should choose sensitive drugs based on the results of drug susceptibility tests to reduce the migration of bacteria.
卢小焕. 115例化脓性角膜炎患者病原菌学及感染危险因素研究[J]. 哈尔滨医药, 2023, 43(3): 33-35.
Lu Xiaohuan. Study on Pathogenic Bacteria and Infection Risk Factors in 115 Patients with Suppurative Keratitis. journal1, 2023, 43(3): 33-35.
2023, Vol. 43 
