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哈尔滨医药  2023, Vol. 43 Issue (6): 26-28    DOI: 10.3969/j.issn.1001-8131.2023.06.010
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关节镜下清理术联合关节腔内注射玻璃酸钠对膝骨关节炎患者膝关节功能的影响
徐昌财1, 李才平2
1.江西省乐平城北医院, 江西 乐平 333300;
2.江西省乐平大连医院, 江西 乐平 333314
Effect of Arthroscopic Debridement Combined with Intra Articular Injection of Sodium Hyaluronate on Knee Function in Patients with Knee Osteoarthritis
Xu Changcai1, Li Caiping2
1. Chengbei Hospital of Leping, Jiangxi Leping 333300, China;
2. Dalian Hospital of Leping, Jiangxi Leping 333314, China
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摘要 目的 探讨关节镜下清理术联合关节腔内注射玻璃酸钠对膝骨关节炎(KOA)患者膝关节功能的影响。方法 选择88例KOA患者, 按随机数字表法分为对照组(44例)与治疗组(44例)。对照组单一行关节镜下清理术治疗, 在此基础上, 治疗组行关节腔内注射玻璃酸钠治疗。对比两组疗效、炎症反应、膝关节功能、并发症、疼痛程度。结果 与对照组相比, 治疗组总有效率高(P< 0.05); 术后两组lysholms评分高于术前, 视觉模拟评分法(VAS)评分较术前低, 而治疗组lysholms评分较对照组高, VAS评分较对照组低(P< 0.05); 术后两组白介素1β (IL-1β )、肿瘤坏死因子-α (TNF-α )、白介素6(IL-6)检测值均低于术前, 治疗组各指标检测值较对照组低(P< 0.05); 组间并发症发生率对比, 差异无统计学意义(P> 0.05)。结论 关节腔内注射玻璃酸钠、关节镜下清理术联合治疗KOA可增强疗效, 降低炎症因子水平, 缓解疼痛, 促进膝关节功能改善, 安全性较高。
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徐昌财
李才平
关键词 膝骨关节炎玻璃酸钠关节镜下清理术膝关节功能    
AbstractObjective To investigate the effect of arthroscopic cleanup combined with intra-articular injection of sodium vitrate on knee joint function in patients with knee osteoarthritis(KOA). Methods 88 patients with KOA were selected and divided into a control group(44 cases)and a treatment group(44 cases)according to the random number table method.The control group was treated with a single arthroscopic debridement, and on this basis, the treatment group was treated with intra-articular injection of sodium vitrate.The efficacy, inflammatory response, knee function, complications, and pain level of the two groups were compared. Results Compared with the control group, the total effective rate of treatment was higher in the treatment group(P< 0.05); postoperative lysholms scores were higher and visual analog scoring method(VAS)scores were lower in the two groups than before surgery, while lysholms scores were higher and VAS scores were lower in the treatment group than in the control group(P< 0.05); postoperative interleukin 1β (IL-1β ), tumor necrosis factor-α (TNF-α )and interleukin-6(IL-6)were lower than those before surgery in both groups, and the values of each index were lower in the treatment group than in the control group(P< 0.05); there was no statistical difference in the incidence of complications between the groups(P> 0.05). Conclusion The combined treatment of KOA with intra-articular injection of sodium vitrate and arthroscopic debridement can enhance the efficacy, reduce the level of inflammatory factors, relieve pain, and promote the improvement of knee function with high safety.
Key wordsknee osteoarthritis    Sodium hyaluronate    Arthroscopic debridement    Knee function
收稿日期: 2023-06-29     
PACS:  R684  
引用本文:   
徐昌财, 李才平. 关节镜下清理术联合关节腔内注射玻璃酸钠对膝骨关节炎患者膝关节功能的影响[J]. 哈尔滨医药, 2023, 43(6): 26-28.
Xu Changcai, Li Caiping. Effect of Arthroscopic Debridement Combined with Intra Articular Injection of Sodium Hyaluronate on Knee Function in Patients with Knee Osteoarthritis. journal1, 2023, 43(6): 26-28.
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