Abstract：Objective To explore the relationship between preoperative immune inflammatory index（SII）and postoperative recurrence of high intensity focused ultrasound（HIFU）in patients with adenomyosis.Methods 120 patients with adenomyosis who underwent physical examination were randomLy selected and divided into relapse group（21 cases）and non-relapse group（99 cases）according to the recurrence situation.Kaplan-Meier method was used to draw the recurrence curve.The clinical data of recurrent group and non-recurrent group within 1 year after operation were compared.The risk factors of recurrence within one year after operation were analyzed by binary logistic regression.Pearson and Kendall analyzed the relationship between preoperative SII and independent influencing factors of recurrence within one year after operation.Results All the 120 patients were followed up,and 21 cases recurred within one year after operation,with a recurrence rate of 17.50%.The comparison of demographic data showed that there were significant differences in age,uterine volume,uterine cavity operation number,lesion type,ablation rate and preoperative SII between recurrent group and non-recurrent group（P<0.05）.Multivariate logistic regression analysis showed that age≥35,preoperative uterine volume≥200,preoperative focus type,high preoperative SII and high preoperative uterine cavity operation were independent risk factors for recurrence within one year after operation（OR=27.424,11.976,39.553,1.110,11.357,P<0.05）.Pearson and Kendall analysis showed that preoperative SII was positively correlated with age,preoperative uterine volume and ablation rate（P<0.05）.However,there was no correlation with preoperative lesion type and preoperative uterine cavity operation（P>0.05）.Conclusion Multivariate logistic regression analysis shows that age ≥35 years old,preoperative uterine volume≥200 cm,preoperative focus type,high preoperative SII and high preoperative uterine cavity operation number are independent risk factors affecting postoperative recurrence,while high ablation rate is a protective factor,and preoperative SII is positively correlated with age,preoperative uterine volume and ablation rate,so preoperative SII can be used as one of the important indexes to predict postoperative recurrence of adenomyosis after HIFU.
陈荣荣, 徐经安, 王俊华. 子宫腺肌病术前免疫炎症指数与高强度聚焦超声术后复发的关系研究[J]. 哈尔滨医药, 2025, 45(2): 21-25.
Chen Rongrong, Xu Jingan, Wang Junhua. Study on the Relationship between Preoperative Immune Inflammatory Index and Postoperative Recurrence of Adenomyosis. journal1, 2025, 45(2): 21-25.
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2025, Vol. 45 
