Abstract：Objective to investigate the effect of vacuum-assisted minimally invasive rotary excision(VAB) under ultrasound in the treatment of benign breast tumors. Methods 80 patients with benign breast tumors treated in our hospital from July 2020 to June 2023 were selected and divided into 40 cases each in the control group(open surgery) and the study group(VAB) by applying the method of random number table,comparing the surgical indexes,pain factors [Neuropeptide Y(NPY),5-Hydroxytryptophan(5-HT),Prostaglandin E2(PGE2)],Visual Analog Scale(VAS) score,tumor markers [carcinoembryonic antigen(CEA),glycan antigen 125(CA125)],and complications. Results Surgical time,incision length,and bleeding were lower in the study group than in the control group,and the differences were statistically significant(P<0.05).Preoperatively,the difference between the two pain factors was not statistically significant(P>0.05);3d postoperatively,NPY,5-HT,and PGE2 were elevated in both groups,and NPY,5-HT,and PGE2 were higher in the control group than in the study group,with statistically significant differences(P<0.05).Postoperatively,VAS was lower in the study group than in the control group in 1d,3d and 7d,and the difference was statistically significant(P<0.05).Preoperatively,the difference between the two tumor markers was not statistically significant(P>0.05);postoperatively,CEA and CA125 were reduced in both groups,and the difference was statistically significant(P<0.05);the difference in CEA and CA125 between the groups was not statistically significant(P>0.05).Complications in the study group were lower than those in the control group,and the difference was statistically significant(P<0.05). Conclusion Benign breast tumors treated with VAB can reduce the degree of pain,promote recovery,and have no effect on tumor markers.
吴云. 超声下真空辅助微创旋切治疗乳腺良性肿瘤疗效及对肿瘤标志物的影响[J]. 哈尔滨医药, 2026, 46(4): 17-19.
Wu Yun. Efficacy of Vacuum-assisted Minimally Invasive Rotational Excision for Benign Breast Tumors under Ultrasound and Its Effect on Tumor Markers. journal1, 2026, 46(4): 17-19.
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2026, Vol. 46 
