Abstract：Objective To explore the application value of white blood cell（WBC）neutrophilic granulocyte（GRA%）,C - reactive protein（CRP）and procalcitonin（PCT）in early diagnosis of neonatal sepsis.Methods Retrospective and analysis of the clinical data of 99 cases full-term neonates treatedin our hospital ,45 children diagnosed with neonatal were sepsiswere served as the observation group ,while another 54 non-infectious children hospitalized during the same period were served as the control group.The levels of the blood WBC、GRA%、CRP、PCT were evaluated in each group,both of the levels of the blood WBC、GRA%、CRP、PCTwere evaluated in observation group before and after treatment for one week.Then analyze the application value of WBC、GRA%、CRP、PCT in early diagnosis ofneonatal sepsis by drawing the receiver operating characteristic curve（ROC curve）.Results The levels of the blood WBC、GRA%、CRP and PCT in the observation group were higher than those in the control group（P<0.05）.The levels of the blood WBC、GRA%、CRP and PCT in the observation group were reduced after treated one week（P<0.05）.The area diagnose neonatal sepsis under the ROC curve of WBC,GRA%,CRP and PCT were 0.722,0.887,0.908,0.964,respectively.Conclusion The dynamic monitoring of blood WBC,GRA%,CRP and PCT has a certain reference value for the treatment of neonatal sepsis.The blood WBC has the lowest diagnostic efficiency in diagnose neonatal sepsis ,the detection of the PCT,CRP,GRA% has a good diagnostic value for neonatal sepsis.
巫福娟, 周成, 张李霞, 戴怡蘅, 高晓燕. WBC、GRA%、CRP与PCT在新生儿败血症早期诊断中的应用[J]. 哈尔滨医药, 2022, 42(3): 26-28.
Wu Fujuan, Zhou Cheng, Zhang Lixia, Dai Yiheng, Gao Xiaoyan. To Explore the Application Value of Blood WBC、GRA%、CRP and PCT in Early Diagnosis of Neonatal Sepsis. journal1, 2022, 42(3): 26-28.
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2022, Vol. 42 
