Effect of Flexible Ureteroscope Holmium Laser Lithotripsy and Percutaneous Nephrolithotomy on Postoperative Inflammatory Response in Patients With Complex Upper Ureteral Calculi
Ma Pengde, Sha Wen, Ji Chuanbiao, Liu Lin, Lu Caiguang, Wu Xinwei, Huang Changming
Department of Urology,Puyang Oilfield General Hospital,Puyang 457000,China
Abstract：Objective To explore the effects of flexible ureteroscope holmium laser lithotripsy and percutaneous nephrolithotomy on postoperative inflammatory response in patients with complex upper ureteral calculi. Methods Totally 70 patients with complex upper ureteral calculi admitted to this hospital were selected for retrospective analysis,and the patients were divided into flexible ureteroscope holmium laser lithotripsy group（the flexible ureteroscope group,35 cases）and percutaneous nephrolithotomy group（the nephroscope group,35 cases）.The effects of the two surgical methods and the influence on postoperative inflammatory response of patients were compared and analyzed. Results There were no significant differences in the incidence rates of postoperative blood loss and infection between the two groups（P>0.05）.The surgical time in the flexible ureteroscope group was significantly longer than that in the nephroscope group（P<0.05）,and the intraoperative blood loss and hospitalization cycle were significantly shorter than those in the nephroscope group（P<0.05）.Compared with before surgery,the peripheral blood white blood cell count（WBC）,C-reactive protein（CRP）,cortisol（Cor）,interleukin-6（1L-6）and interleukin-10（1L-10）in the two groups were significantly improved（P<0.05）,but the increases of various indicators of inflammatory response in the flexible ureteroscope group were significantly lower than those in the nephroscope group（P<0.05）. Conclusion Flexible ureteroscope holmium laser lithotripsy has milder body’ s inflammatory response than percutaneous nephrolithotomy in the treatment of complex upper ureteral calculi,and it can shorten the hospitalization cycle,and has less intraoperative blood loss and much safety.
2021, Vol. 41 
