多b值DWI与T2 mapping定量技术诊断前列腺癌与前列腺增生结节价值研究

doi:10.3969/j.issn.1001-8131.2026.01.002

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Abstract Objective To investigate the diagnostic value of multi-b-value diffusion-weighted imaging(DWI)and T2 mapping quantitative parameters in differentiating prostate cancer(PCa)from benign prostatic hyperplasia(BPH). Materials and Methods A retrospective analysis was conducted on imaging data from 67 pathologically confirmed PCa patients and 66 BPH patients who underwent MR examination in our hospital.ADC values from DWI at b=1000 and 2000 s/mm² and T2 mapping values were measured in both groups.Differences in ADC values at different b-values and T2 values between the two groups were compared. Results Operating characteristic(ROC)curve analysis was used to evaluate the diagnostic performance of each parameter and the combined ADC₂₀₀₀-T2 model. Results The ADC₁₀₀₀,ADC₂₀₀₀,and T2 values in the PCa group were significantly lower than those in the BPH group,with statistically significant differences(P<0.01).The AUC values for differentiating PCa from BPH were 0.80 for ADC₁₀₀₀,0.83 for ADC₂₀₀₀,0.89 for T2 value,and 0.92 for the combined ADC₂₀₀₀-T2 model.The diagnostic performance of the combined ADC₂₀₀₀-T2 mapping model was superior to that of ADC₁₀₀₀ or ADC₂₀₀₀alone,and the difference was statistically significant. Conclusion Quantitative parameters from DWI and T2 mapping sequences demonstrate good diagnostic value in differentiating PCa from BPH.Moreover,the combined model incorporating high b-value DWI and T2 mapping further improves diagnostic performance,providing a reliable basis for the clinical diagnosis of PCa.

Key words： Prostate Cancer Prostatic Hyperplasia Diffusion-weighted Imaging T2 Mapping Imaging

Received: 04 February 2026

PACS:

R737.25

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	Articles by authors
	Wang Xu
	Chen Ting
	Wang Shan
	Xie Xiaoping

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Wang Xu,Chen Ting,Wang Shan, et al. Study on the Value of Multi-b-value DWI and T2 Mapping Quantitative Techniques in the Diagnosis of Prostate Cancer and Benign Prostatic Hyperplasia Nodules[J]. journal1, 2026, 46(1): 4-7.

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http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2026.01.002 OR http://www.hrbyybjb.org.cn/EN/Y2026/V46/I1/4

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