OSAHS患儿应用鼻内镜下腺样体低温等离子消融术治疗对其免疫功能的影响

doi:10.3969/j.issn.1001-8131.2022.02.003

Abstract
Figure/Table
References
Related Citation (13)

Download: PDF (388 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the effects of nasal endoscopic low-temperature plasma ablation of adenoid on immune function in children with obstructive sleep apnea-hypopnea syndrome（OSAHS）.Methods A total of 88 children confirmed with OSAHS in the hospital were enrolled.According to simple random grouping method,they were divided into observation group and control group,44 cases in each group.The control group underwent adenoid dissection,while observation group was treated with nasal endoscopic low-temperature plasma ablation of adenoid.After surgery,curative effect between the two groups was compared.The serum immunoglobulin G（IgG）,immunoglobulin A（IgA）and immunoglobulin M（IgM）were detected by enzyme linked immunosorbent assay.The peripheral blood T lymphocyte subsets（CD3⁺,CD4⁺,CD8⁺,CD4⁺/CD8⁺）were detected by Beckman flow cytometry.The occurrence of postoperative complications in both groups was observed and recorded.Results The difference in total response rate of treatment between observation group and control group was not statistically significant（93.18% vs 86.36%）（P>0.05）.After surgery,levels of serum IgG,IgA and IgM,and peripheral blood CD3⁺,CD4⁺ and CD4⁺/CD8⁺ in observation group were significantly higher than those in control group（P<0.05）.The difference in incidence of postoperative complications between observation group and control group was not statistically significant（2.27% vs 11.36%）（P>0.05）.Conclusion There is no difference in curative effect and complications between nasal endoscopic low-temperature plasma ablation of adenoid and adenoid dissection in the treatment of OSAHS children,with few effects on immune function.

Key words： Obstructive sleep apnea-hypopnea syndrome Low-temperature plasma ablation Immune function

Received: 12 December 2020

PACS:

R762

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Li Ying

Cite this article:

Li Ying. Effects of Nasal Endoscopic Low-Temperature Plasma Ablation of Adenoid on Lmmune Function in OSAHS Children[J]. journal1, 2022, 42(2): 8-10.

URL:

http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2022.02.003 OR http://www.hrbyybjb.org.cn/EN/Y2022/V42/I2/8

[1] 高淑蔚,郭永丽,许志飞.阻塞性睡眠呼吸暂停综合征儿童腺样体扁桃体切除术后治疗效果及其预测因素的研究进展[J].中华耳鼻咽喉头颈外科杂志,2020,55(6):630-634.
[2] 边晓敏,韩光红,刘岩,等.儿童阻塞性睡眠呼吸暂停低通气综合征与多系统疾病的相关性研究进展[J].中国耳鼻咽喉头颈外科,2019,26(6):45-48.
[3] 朱友莲,谢婷,黄惠玲,等.鼻内镜辅助腺样体低温等离子消融术与切除术治疗小儿腺样体肥大的疗效对比[J].中国妇幼保健,2017,32(7):1584-1587.
[4] 李柏滋,吴树浓,卢坚,等.鼻内镜下低温等离子射频消融术治疗儿童OSAHS的价值探讨[J].新医学,2019,50(2):134-138.
[5] 中华耳鼻咽喉头颈外科杂志编委会,中华医学会耳鼻咽喉科学分会.儿童阻塞性睡眠呼吸暂停低通气综合征诊疗指南草案(乌鲁木齐)[J].中华耳鼻咽喉头颈外科杂志,2007,42(2):83-84.
[6] 叶京英,李五一.阻塞性睡眠呼吸暂停低通气综合征诊断和外科治疗指南[J].中华耳鼻咽喉头颈外科杂志,2009,44(2):91-94.
[7] 张丽芳,张学强,秦君.低温等离子消融术对OSAHS儿童免疫功能的影响[J].宁夏医科大学学报,2019,41(2):186-188.
[8] 马菁茹,黄晶晶,肖宽林.儿童阻塞性睡眠呼吸暂停低通气综合征与常见炎症因子及相关疾病的关系[J].中国眼耳鼻喉科杂志,2017,17(5):366-369.
[9] 康子威,卫来,王志强.腺样体肥大手术治疗的研究进展[J].海南医学,2019,30(19):2566-2569.
[10] 刘平,闫亚平,崔程敏,,等.低温等离子射频消融术与电动切割器切除腺样体疗效分析[J].中国耳鼻咽喉头颈外科,2020,27(11):661-662.
[11] 朱友莲,谢婷,黄惠玲,等.鼻内镜辅助腺样体低温等离子消融术与切除术治疗小儿腺样体肥大的疗效对比[J].中国妇幼保健,2017,32(7):1584-1587.
[12] 张国顺,黄晓阳,李守民,等.鼻内镜下腺样体低温等离子消融术与切割术的短期疗效比较及对咽鼓管功能的影响[J].中国耳鼻咽喉头颈外科,2017,24(4):194-197.
[13] 仇书要,刘大波,钟建文,等.儿童腺样体及扁桃体低温等离子消融术后腭瘘一例[J].中华耳鼻咽喉头颈外科杂志,2017,52(2):113-114.
[14] 赵红,于湛,王鹏,等.低温等离子消融技术行腺样体扁桃体手术的围手术期护理[J].中国疗养医学,2011,20(4):352-353.
[15] 金书香,王吉喆,曲慧.腺样体、扁桃体切除术对OSAHS患儿免疫功能的影响[J].临床耳鼻咽喉头颈外科杂志,2017,31(23):1810-1814.

[1]	. [J]. journal1, 2022, 42(1): 70-71.
[2]	. [J]. journal1, 2021, 41(6): 58-59.
[3]	. [J]. journal1, 2021, 41(6): 72-73.
[4]	. [J]. journal1, 2021, 41(6): 76-77.
[5]	. [J]. journal1, 2021, 41(5): 139-140.
[6]	Liang Menglin, Huang Xiangmin, Tan Xiong. Effect of Vitamin AD on Children With Recurrent Respiratory Tract Infection[J]. journal1, 2021, 41(4): 21-23.