子宫腺肌病术前免疫炎症指数与高强度聚焦超声术后复发的关系研究

doi:10.3969/j.issn.1001-8131.2025.02.007

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (698 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the relationship between preoperative immune inflammatory index（SII）and postoperative recurrence of high intensity focused ultrasound（HIFU）in patients with adenomyosis.Methods 120 patients with adenomyosis who underwent physical examination were randomLy selected and divided into relapse group（21 cases）and non-relapse group（99 cases）according to the recurrence situation.Kaplan-Meier method was used to draw the recurrence curve.The clinical data of recurrent group and non-recurrent group within 1 year after operation were compared.The risk factors of recurrence within one year after operation were analyzed by binary logistic regression.Pearson and Kendall analyzed the relationship between preoperative SII and independent influencing factors of recurrence within one year after operation.Results All the 120 patients were followed up,and 21 cases recurred within one year after operation,with a recurrence rate of 17.50%.The comparison of demographic data showed that there were significant differences in age,uterine volume,uterine cavity operation number,lesion type,ablation rate and preoperative SII between recurrent group and non-recurrent group（P<0.05）.Multivariate logistic regression analysis showed that age≥35,preoperative uterine volume≥200,preoperative focus type,high preoperative SII and high preoperative uterine cavity operation were independent risk factors for recurrence within one year after operation（OR=27.424,11.976,39.553,1.110,11.357,P<0.05）.Pearson and Kendall analysis showed that preoperative SII was positively correlated with age,preoperative uterine volume and ablation rate（P<0.05）.However,there was no correlation with preoperative lesion type and preoperative uterine cavity operation（P>0.05）.Conclusion Multivariate logistic regression analysis shows that age ≥35 years old,preoperative uterine volume≥200 cm,preoperative focus type,high preoperative SII and high preoperative uterine cavity operation number are independent risk factors affecting postoperative recurrence,while high ablation rate is a protective factor,and preoperative SII is positively correlated with age,preoperative uterine volume and ablation rate,so preoperative SII can be used as one of the important indexes to predict postoperative recurrence of adenomyosis after HIFU.

Key words： adenomyosis Preoperative Immune inflammatory index High intensity focused ultrasound recur

Received: 18 February 2025

PACS:

R711.74

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Chen Rongrong
	Xu Jingan
	Wang Junhua

Cite this article:

Chen Rongrong,Xu Jingan,Wang Junhua. Study on the Relationship between Preoperative Immune Inflammatory Index and Postoperative Recurrence of Adenomyosis[J]. journal1, 2025, 45(2): 21-25.

URL:

http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2025.02.007 OR http://www.hrbyybjb.org.cn/EN/Y2025/V45/I2/21

[1] BULUN SE,YILDIZ S,ADLI M,et al.Endometriosis and adenomyosis:shared pathophysiology[J].Fertil Steril.2023;119(5):746-750.
[2] YAN L,HUANG H,LIN J,YU R.High-intensity focused ultrasound treatment for symptomatic uterine fibroids:a systematic review and meta-analysis[J].Int J Hypert-hermia.2022;39(1):230-238.
[3] 王丹,金卓婷,王李纲,等.高强度聚焦超声联合热球子宫内膜消融治疗子宫腺肌病相关月经过多的临床研究[J].实用妇产科杂志,2024,40(7):560-565.
[4] 范丽,史小荣.高强度聚焦超声治疗子宫腺肌症的研究进展[J].安徽医药,2024,28(1):22-26.
[5] MORISHIMA Y,UENO Y,SATAKE A,et al.Recurrent embolic stroke associated with adenomyosis:A single case report and literature review[J].Neurol Sci.2023;44(7):2421-2429.
[6] CUADRADO-TORROGLOSA I,GARCíA-VELASCO JA,ALECSANDRU D.The Impacts of Inflammatory and Autoimmune Conditions on the Endometrium and Re-productive Outcomes[J].J Clin Med.2024;13(13):3724.
[7] DONG Y,CHEN Y,WANG Y,et al.Correlation between the Systemic Immunoinflammatory Index and Platelet-Lymphocyte Ratio in Patients with Adenomyosis[J].Mediators Inflamm.2024;2024:9977750.
[8] 中国医师协会妇产科医师分会子宫内膜异位症专业委员会.子宫腺肌病诊治中国专家共识[J].中华妇产科杂志,2020,55(6):376-383.
[9] SEIJI WATANABE,KANJI KOYAMA.Visual Analogue Pain Scale with Convenient Digitizer[J].Anesthesiology,1989,71(3):481-485.
[10] 杨超逸,谭爱丽.临床特征在术前诊断子宫腺肌病合并子宫内膜癌中的作用[J].安徽医科大学学报,2024,59(5):885-889.
[11] 赵明阳,宋学薇,贾凡,等.HIFU与UAE治疗不同分型子宫腺肌症的疗效分析[J].中国性科学,2024,33(7):61-66.
[12] 许莉莉,黄静,黄凤叶,等.高强度聚焦超声治疗再发性子宫腺肌病的疗效观察[J].临床超声医学杂志,2024,26(8):647-650.
[13] 宋学薇,赵明阳,贾凡,等.高强度聚焦超声和子宫动脉栓塞术治疗不同分型子宫腺肌病患者的临床研究[J].中国性科学,2024,33(12):70-75.
[14] 赵博,赵敏.仙蓉合剂联合左炔诺孕酮宫内释放系统对子宫腺肌病患者血清免疫-炎症指数全身炎症反应指数糖类抗原125的影响[J].中国药物与临床,2023,23(8):535-539.
[15] ZHAO Y,SHAO W,ZHU Q,et al.Association between systemic immune-inflammation index and metabolic syndrome and its components:results from the National Health and Nutrition Examination Survey 2011-2016[J].J Transl Med.2023;21(1):691.
[16] 师帅,姜虹,李勤,等.高强度聚焦超声消融治疗(HIFU术)联合补肾活血方治疗子宫腺肌病的临床研究[J].现代生物医学进展,2023,23(21):4120-4124.
[17] 张满丽. HIFU治疗子宫腺肌病术后复发影响因素分析[D].成都中医药大学,2023.
[18] 戚莹莹,何月明,明方华,等.基于JAK2/STAT3信号通路探讨高强度聚焦超声治疗子宫腺肌病机制的实验研究[J].现代肿瘤医学,2023,31(20):3722-3729.
[19] 汪沙,段华.高强度聚焦超声消融治疗子宫腺肌病的研究进展[J].中华生殖与避孕杂志,2024,44(1):90-93.
[20] 艾星子·艾里,郭铮宇,张晓霏.子宫腺肌病高强度聚焦超声消融治疗研究进展[J].山东大学学报(医学版),2022,60(7):36-42.