厄贝沙坦氢氯噻嗪联合美托洛尔在老年心力衰竭患者中的应用价值分析

doi:10.3969/j.issn.1001-8131.2023.05.002

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Abstract Objective To explore the efficacy of Irbesartan hydrochlorothiazide combined with metoprolol in elderly patients with heart failure.Methods 74 elderly patients with heart failure were selected and divided into a combination group（n=37）and a single group（n=37）according to the random number table method.The single group was given metoprolol,and the combined group was given metoprolol + Irbesartan hydrochlorothiazide.The curative effect,B-type brain natriuretic peptide（BNP）,heart rate（HR）,6-min walking test,high-sensitivity C-reactive protein（hs-CRP）level and adverse reactions were compared between the two groups.Results Compared with 72.97%（27/37）of the single group,the total effective rate of the combined group94.59%（35/37）washigher（P<0.05）;Compared with the single group,the HR of the combined group after treatment was lower,the 6-min walking test was longer,and the levels of BNP and hs-CRP were lower（P<0.05）;The incidence of adverse reactions in the combined group 8.11%（3/37）was lower than that in the single group 27.03%（10/37）（P<0.05）.Conclusion Irbesartan and hydrochlorothiazide combined with metoprolol in the treatment of elderly patients with heart failure can improve the curative effect,improve thecardiac function,and cardiac function,and is safe and reliable.

Key words： heart failure Irbesartan hydrochlorothiazide metoprolol

Received: 29 September 2022

PACS:

R541.6+1

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	He Lei
	Xing Ying
	Wang Haiyang

Cite this article:

He Lei,Xing Ying,Wang Haiyang. Analysis of Application Value of Irbesartan Hydrochlorothiazide Combined with Metoprolol in Elderly Patients with Heart Failure[J]. journal1, 2023, 43(5): 4-6.

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http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2023.05.002 OR http://www.hrbyybjb.org.cn/EN/Y2023/V43/I5/4

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