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| Effects of Vaginal Myomectomyand Laparoscopic Myomectomy on Estrogen Receptor, Sex Hormone and Quality of Sexual Life in Patients with Uterine Fibroid |
| Cao Meng, Chang Lu, Hao Yujuan, Tang Zhihui |
| Obstetrics and Gynecology Department, Xuchang Central Hospital, Xuchang, 461000, Henan |
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Abstract Objective To observe the effects of vaginal myomectomy（VM）and laparoscopic myomectomy（LM）on estrogen receptor, sex hormone and sex life quality in patients with uterine fibroids（UF）. Methods A total of 100 UF patients were selected as research objects and divided into LM group and VM group according to block randomization, with 50 cases in each group.The LM group was treated with LM and the VM group was treated with VM.The basic information of the two groups during perioperative period（operation time, blood loss, first anal exhaust time）was compared, and the changes of ER, sex hormones（FSH, LH, E2）before and 1 week after surgery were compared between the two groups.The incidence of postoperative complications in the two groups was counted 1 week after surgery, and the quality of sexual life（sexual life quality scale）was observed in the two groups before surgery and 1 month after surgery. Results The operation time, blood loss and first anal exhaust time in VM group were lower than those in LM group（P< 0.05）.One week after surgery, the levels of FSH and LH in both groups were increased compared with those before surgery（P< 0.05）, and the positive rate of ER and the level of E2 were decreased compared with those before surgery（P< 0.05）.There was no significant difference between the two groups（P> 0.05）.The incidence of postoperative complications in VM group was lower than that in LM group（P< 0.05）.One month after surgery, the sex life quality scale scores in both groups were higher than those before surgery（P< 0.05）, and the VM group was higher than the LM group at the same period（P< 0.05）. Conclusions Both VM and LM can effectively treat UF and improve the levels of estrogen receptor and sex hormone in patients.Compared with LM, VM has shorter operation time, less postoperative blood loss and postoperative complications, which is more conducive to improving the quality of sexual life of patients.
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Received: 12 December 2022
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2023, Vol. 43 
