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| The Anesthetic Effect of Alfentanil Combined with Cyclopofol in Gynecological Hysteroscopic Surgery and Its Influence on Postoperative Recovery |
| Liang Min, Zhang Hongting, Guo Yijie, Li Yunfan |
| Anesthesiology Department,Lianjiang People's Hospital,524400 |
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Abstract Objective To explore the anesthetic effect of alfentanil combined with propofol in gynecological hysteroscopic surgery and its influence on postoperative recovery. Methods According to the inclusion and exclusion criteria,82 patients who underwent gynecological hysteroscopic surgery were selected as the research subjects and a grouped controlled study was conducted on them.The grouping method was the random number table method,and they were divided into two groups,namely the control group and the observation group,with 41 cases in each group.The control group was given alfentanil combined with propofol anesthesia.The observation group was anestheted with alfentanil combined with cyclopofol during the operation.The anesthesia effects,vital signs,quality of anesthesia recovery,sedation and analgesia before and after the operation,cognitive conditions and the incidence of adverse reactions were compared between the two groups. Results The excellent and good rate of anesthesia in the observation group was higher than that in the control group(P<0.05).The heart rate(HR)and mean arterial pressure(MAP)of the two groups at 3 minutes after administration(T1)and during cervical dilation(T2)were lower than those at the T0 time point(P<0.05),and there was no statistical difference in HR and MAP at different time points between the two groups(P>0.05).The anesthesia induction,orientation recovery,eye opening and breathing recovery time in the observation group were shorter than those in the control group(P<0.05).The scores of the Alert/Sedation observation group(OAA/S)and the Mini-Mental State Examination(MMSE)6 hours after the operation in the observation group were higher than those in the control group.The Visual Analogue Scale(VAS)for pain was lower than that of the control group(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05). Conclusion For patients undergoing gynecological hysteroscopic surgery,the use of alfentanil combined with cyclopofol anesthesia can not only effectively improve the anesthetic effect,reduce the impact on their vital signs,but also promote their postoperative recovery,enhance their sedative and analgesic effects,promote the recovery of their cognitive function,and reduce the incidence of adverse reactions.
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Received: 03 June 2025
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