|
|
|
| Results of Coagulation Function Monitoring in Premature Infants of Different Gestational Ages and Their Correlation With Hemorrhagic Disease |
| Li Lina |
| Paediatrics of General Hospital of Puyang Oilfield,Puyang 457000,China |
|
|
|
|
Abstract Objective To explore the results of coagulation function monitoring in premature infants of different gestational ages and their correlation with hemorrhagic disease.Methods A total of 120 premature infants were included in the study.According to the difference in gestational age,they were divided into small-gestational-age premature infant group(≤34 weeks,n=51) and large-gestational-age premature infant group (>34 weeks and <37 weeks,n=69).The fibrin degradation products (FDP),fibrinogen (FIB),prothrombin time (PT),activated partial thromboplastin time (APTT),D-dimer (DD) and other coagulation function indicators were monitored and analyzed at 2h after delivery,and the correlation between different gestational ages and hemorrhagic disease was analyzed.Results There were no significant differences in gender and delivery methods between small-gestational-age premature infant group and large-gestational-age premature infant group(P>0.05).The gestational age and body mass in small-gestational-age premature infant group was lower than those in large-gestational-age premature infant group (P<0.05).The levels of FDP,PT,APTT and DD in small-gestational-age premature infant group were higher than those in large-gestational-age premature infant group(P<0.05).The FIB level in small-gestational-age premature infant group was lower than that in large-gestational-age premature infant group(P<0.05).The total incidence rate of bleeding in small-gestational-age premature infant group was higher than that in large-gestational-age premature infant group (15.69% vs.2.89%) (P<0.05).Conclusion The results of coagulation function monitoring are different among premature infants of different gestational ages,and premature infants of small gestational ages are prone to hemorrhagic disease.Thus it is necessary to strengthen the coagulation function monitoring and strictly pay attention to patients of small gestational ages,so as to effectively prevent the occurrence of hemorrhagic disease.
|
|
Received: 10 September 2020
|
|
|
|
|
|
[1] 高亮,林新祝,吴倩倩,等.不同胎龄早产儿凝血功能及出血性疾病的临床研究[J].中国当代儿科杂志,2019,21(2):120-124.
[2] 赵娟,张丙宏.出生胎龄及体质量与新生儿凝血功能的关系[J].中国医师进修杂志,2017,40(8):686-689.
[3] 付海波,徐静.不同胎龄足月儿临床转归研究[J].中国现代医学杂志,2018,28(6):114-117.
[4] 宋小燕,陈红武,廖卫华,等.持续脑功能监测评估亚低温治疗缺氧缺血性脑病新生儿预后的临床价值[J].中华新生儿科杂志(中英文),2018,33(1):7-11.
[5] 方小红,许丽萍,林丽聪,等.早产儿脑损伤的影响因素研究[J].中国全科医学,2017,20(4):459-464.
[6] 朱晶文,张雪峰.新生儿出生后24小时内凝血功能检测的临床意义分析[J].发育医学电子杂志,2020,8(2):157-162. |
| [1] |
. [J]. journal1, 2021, 41(5): 84-85. |
| [2] |
. [J]. journal1, 2021, 41(4): 72-73. |
| [3] |
. [J]. journal1, 2021, 41(2): 143-144. |
|
|
|
|
2021, Vol. 41 
