小剂量尿激酶治疗急性轻型脑梗死的临床研究

doi:10.3969/j.issn.1001-8131.2022.01.001

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Abstract Objective To study the clinical effect of low-dose urokinase in patients with acute cerebral infarction. Methods 50 patients were selected for study,divided into study group and routine group,25 cases in each group.Both groups were treated for 2 weeks,and the total effective rate was calculated.The neurological deficit score scale（NIHSS）and the modified Rankin score,Barth index（BI）,and activity of daily living（ADL）were used to treat the patient's nerves.The function,as well as the quality of life and daily living ability,are assessed.The plasma viscosity,high and low cut whole blood viscosity,and fibrinogen（FIB）levels were compared before and after treatment. Results After comparison,the NIHSS score and the improved Rankin（mRS）score of the study group were much better than the conventional group 3 months after treatment,P<0.05,the difference between the groups was statistically significant.There was no significant difference in the incidence of complications between the two groups,P>0.05,the difference was not statistically significant.The daily living ability and quality of life of the two groups were compared.The study group was far superior to the conventional group,P<0.05,and the difference was statistically significant.The changes of platelet counts before and after treatment in the two groups were compared.There were significant differences in the levels of the indicators before and after treatment in the study group,P<0.05.has statistical significane.There was no significant difference in platelet counts between the conventional group before and after treatment,P>0.05,and the difference was not statistically significant.Comparing the changes of hematocrit in the two groups before and after treatment,the hematocrit values of the two groups were lower than the treatment before treatment.The decline of the study group was much higher than that of the conventional group.There was a significant difference in the levelofcompressio,P<0.05,thedifference was statistically significant. Conclusion The clinical use of low-dose urokinase can significantly improve the efficacy of patients with acute cerebral infarction,improve the safety of patients,and has a high clinical value.

Key words： Urokinase Acute mild cerebral infarction Neurological deficit score scale

Received: 12 December 2020

PACS:

R743.33

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	Lan Shaoyong
	Lin Dong
	Su Binru

Cite this article:

Lan Shaoyong,Lin Dong,Su Binru. Clinical Study of Low-Dose Urokinase in the Treatment of Acute Mild Cerebral Infarction[J]. journal1, 2022, 42(1): 1-4.

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http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2022.01.001 OR http://www.hrbyybjb.org.cn/EN/Y2022/V42/I1/1

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