|
|
|
| Clinical Effect of Self-Made Huotan Kaiqiao Prescription Combined With Acupuncture in the Treatment of Cerebral Infarction |
| Sun Yuting |
| Zhoukou Central Hospital,Zhoukou 466000,China |
|
|
|
|
Abstract Objective To explore the clinical effect of self-made Huotan Kaiqiao prescription combined with acupuncture in the treatment of cerebral infarction. Methods A total of 84 patients with cerebral infarction who were admitted to the hospital were enrolled.They were divided into study group and control group by random number table method,42 cases in each group.The control group was given routine treatment,while study group was given self-made Huotan Kaiqiao prescription combined with acupuncture on basis of control group.The scores for TCM syndrome,the National Institutes of Health Stroke Scale（NIHSS）,Fugl-Meyer Assessment,Montreal Cognitive Assessment（MoCA）and Activity of Daily Living（ADL）,levels of serum nitric oxide（NO）,plasma endothelin（ET-1）and von Willebrand factor（vWF）,and adverse reactions were compared between the two groups. Results After treatment,improvement of TCM syndrome,NIHSS,and MoCA scores in study group was better than that in control group（P<0.05）,but no significant differences were found between the two groups in FMA and ADL scores（P>0.05）.After treatment,level of serum NO was significantly increased in both groups,which was better in study group than control group（P<0.05）,while levels of serum ET-1 and vWF were significantly decreased,which were better in study group than control group（P<0.05）.The incidence of adverse reactions in study group was lower than that in control group（7.14% vs 28.57%）（P<0.05）. Conclusion The clinical effect of self-made Huotan Kaiqiao prescription combined with acupuncture is significant in the treatment of cerebral infarction,which can significantly improve neurological deficits,motor function,cognitive function,activities of daily living,and vascular endothelial function,with good safety.
|
|
Received: 10 December 2020
|
|
|
|
|
|
[1] 周星娅,刘维红,刘涛,等.针灸治疗脑梗死后痉挛性瘫痪临床选穴规律研究[J].中国中医基础医学杂志,2018,24(7):974-977.
[2] 张柳英,夏章勇,赵鑫,等.缺血性脑卒中侧支循环的研究进展[J].中华老年心脑血管病杂志,2018,20(7):777-780.
[3] 徐耀铭,齐晓飞,王姝瑶,等.急性脑梗死早期进展相关危险因素的临床研究[J].中风与神经疾病杂志,2018,35(6):548-549.
[4] 中国中西医结合学会神经科专业委员会.中国脑梗死中西医结合诊治指南(2017)[J].中国中西医结合杂志,2018,38(2):136-144.
[5] 中风病诊断与疗效评定标准(试行)[J].北京中医药大学学报,1996,19(1):55-56.
[6] Kwah LK,Diong J.National institutes of health stroke scale(NIHSS)[J].J Physiother,2014,60(1):61.
[7] Gladstone DJ,Danells CJ,Black SE.The fugl-meyer ass-essment of motor recovery after stroke:a critical review of its measurement properties[J].Neurorehabil Neural Repair,2002,16(3):232-240.
[8] NaseeddineZS.The montreal cognitive assessment(MOCA):a brief screening tool for mild cognitive impairment[J].J Am Geriatric Soc,2005,53(4):695-699.
[9] Mahoney FI.Functional evaluation:the barthel Index[J].Md State Med J,1965,14(4):61-65.
[10] 宋珏娴,黄礼媛,王细文,等.高利教授采用中西医结合方法诊治脑梗死的思路[J].中国中西医结合急救杂志,2019,(2):233-234.
[11] Xu W,Ning X,Zhang C,et al.Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction[J].Exp Ther Med,2018,15(5):4564-4570. |
| [1] |
Wang Dongfang. Clinical Effect Observation of Esomeprazole in the Treatment of Peptic Ulcer[J]. journal1, 2022, 42(2): 11-13. |
| [2] |
Shao Jingtian, Huang Yan, Huang Lixian. Clinical Observation of Infection Index in Patients With Pulmonary Infection and Fever Treated With Doxycycline[J]. journal1, 2022, 42(2): 14-15. |
| [3] |
. [J]. journal1, 2022, 42(2): 52-54. |
| [4] |
. [J]. journal1, 2022, 42(2): 70-71. |
| [5] |
. [J]. journal1, 2022, 42(2): 123-125. |
| [6] |
Lan Shaoyong, Lin Dong, Su Binru. Clinical Study of Low-Dose Urokinase in the Treatment of Acute Mild Cerebral Infarction[J]. journal1, 2022, 42(1): 1-4. |
|
|
|
|
2022, Vol. 42 
