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| Application of Serum Amyloid A in the Diagnosis of Rotavirus Enteritis in Children |
| Zhao Xiafeng, Yang Xiaohua, Liu Qingfeng |
| Clinical Laboratory,Red Cross Hospital of Guangzhou,Guangzhou 510000,China |
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Abstract Objective To explore the application of serum amyloid A（SAA）in the diagnosis of rotavirus enteritis in children.Methods 120 children with enteritis who were positive for fecal rotavirus by colloidal gold method were selected for retrospective analysis.They were divided into observation group and 120 children with functional diarrhea caused by non infectious causes were selected as control group.The expression level and positive rate of serum SAA in the two groups were compared,The expression level and positive rate of SAA in children with rotavirus enteritis with different degrees of dehydration were analyzed.The corresponding specificity and sensitivity were obtained according to serum SAA.The ordinate was the sensitivity and the abscissa was the specificity.The receiver operating（ROC）curve was drawn to analyze the diagnostic value of SAA in children with rotavirus enteritis.Results There were significant differences in SAA expression and SAA positive rates between the observation group and the control group,and the observation group was significantly higher than the control group（P<0.05）;the SAA expression and SAA positive rates in children with rotavirus enteritis with different degrees of dehydration were significantly different ,And children with severe dehydration were significantly higher than those with mild to moderate dehydration and without dehydration（P<0.05）;the area under the curve of serum amyloid A was 78.89,and the best diagnostic limit was 12.52mg/L.Conclusion The expression level and positive rate of serum amyloid A in children with rotavirus enteritis were significantly higher than those in children with functional diarrhea,and SAA>12.52mg/L was the critical value for the diagnosis of rotavirus enteritis.
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Received: 16 September 2021
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[1] 陈明晶. 小儿腹泻的发病机制及临床治疗研究进展[J].甘肃科技,2020,36(18):132-134.
[2] 李勇冠,李蕊慧,刘菊香.小儿轮状病毒肠炎临床治疗研究[J].母婴世界,2019,(1):86.
[3] 林向荣,郭春梅,韩雪玲,等.轮状病毒肠炎并发良性惊厥患儿医院感染临床特点及危险因素[J].中华医院感染学杂志,2019,29(15):2383-2386.
[4] 朱本辉,李玉霞,谢鹤.不同剂量蒙脱石散治疗儿童轮状病毒肠炎的疗效及对炎症因子的影响研究[J].中国妇幼保健,2019,34(10):2277-2280.
[5] 曹琳,宋晓文,任金来,等.血清淀粉样蛋白A的研究进展[J].安徽医药,2019,23(2):221-224.
[6] 汤伟明,徐燕,芮志莲.血清SAA,CK,ET水平在小儿急性感染性腹泻病情评估中的价值[J].临床输血与检验,2020,22(5):530-532.
[7] 胡秀林. 人血清淀粉样蛋白A和C反应蛋白联合检测在儿科中的应用[J].健康必读,2020,21(3):54.
[8] 杨建伟. PCT及CRP在小儿轮状病毒肠炎中的变化意义[J].齐齐哈尔医学院学报,2019,40(7):844-846.
[9] 王潇. 小儿轮状病毒肠炎176例临床特点分析实践思考[J].中国社区医师,2019,35(9):62-65.
[10] 殷佟,袁博,黄雅玲,等.红细胞免疫及血清炎性因子水平与轮状病毒肠炎患儿脱水程度的关系[J].中国医药导报,2019,16(6):86-89.
[11] 康飞. 降钙素原、C反应蛋白和心肌酶CK-MB检测在轮状病毒性肠炎患儿中的诊断价值探讨[J].中国保健营养,2019,29(6):375.
[12] 金莉,沈梦亮.布拉酵母菌散剂治疗小儿急性腹泻的疗效观察[J].中国基层医药,2018,25(2):161-163.
[13] 滕承志,罗玲玲,张春丽,等.L-谷氨酰胺呱仑酸钠联合埃索美拉唑治疗小儿消化性溃疡疗效及对患儿免疫功能和肠道菌群的影响[J].中国基层医药,2016,23(10):1441-1444. |
| [1] |
. [J]. journal1, 2022, 42(2): 92-94. |
| [2] |
. [J]. journal1, 2022, 42(2): 95-96. |
| [3] |
. [J]. journal1, 2022, 42(2): 107-108. |
| [4] |
. [J]. journal1, 2022, 42(1): 68-69. |
| [5] |
. [J]. journal1, 2021, 41(6): 121-122. |
| [6] |
. [J]. journal1, 2021, 41(6): 114-115. |
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2022, Vol. 42 
