基于中药配方下中药饮片联合颗粒治疗原发性高血压的临床疗效和安全性分析

doi:10.3969/j.issn.1001-8131.2023.01.044

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Abstract Objective To explore the clinical efficacy and safety of Chinese herbal decoction pieces combined with granules in the treatment of essential hypertension based on Chinese herbal formulas.Methods In this study,subjects with essential hypertension were selected and randomly divided into two groups,each with an equal number of 66 cases.The control group was given Chinese medicine decoction pieces,and the observation group was given Chinese medicine granules combined treatment.The efficacy of the two groups of patients was compared;the scores of TCM symptoms,blood pressure and adverse reactions during the treatment of the two groups were recorded;the compliance of the two groups of patients before and after the treatment was observed;the two groups of patients were followed up for one year,and the two groups of patients had adverse events The cumulative incidence was recorded.Results After treatment,by comparing the two groups of TCM symptom scores,it was found that the scores of the two groups were reduced,and the scores of the observation group were lower than those of the control group,but the difference between the two was not significant（P>0.05）;After treatment,both the medication compliance and the total effective rate of the two groups of patients were significantly increased,and the compliance and effective rate of the observation group were significantly better than those of the control group（P<0.05）;Comparing the blood pressure of the two groups,it was found that both systolic and diastolic blood pressures decreased in the two groups,and the decrease in the observation group was more significant（P<0.05）;One-year follow-up found that 5 cases（7.58%）in the observation group had adverse events;13 cases（19.70%）in the control group had adverse events,the difference was statistically significant（P<0.05）.Conclusion For patients with essential hypertension,the clinical efficacy of the treatment of Chinese herbal medicine and the combination of Chinese medicine granules is equivalent,but the blood pressure improvement effect of the combined granules treatment is more significant.In addition,it can improve compliance and has a higher clinical application value.

Key words： Chinese medicine formula Chinese medicine decoction pieces Chinese medicine granules Essential hypertension Efficacy Safety

Received: 03 January 2022

PACS:

R285.6

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	Guo Weiwei
	Yang Li
	Yao Gang

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Guo Weiwei,Yang Li,Yao Gang. Analysis of the Clinical Efficacy and Safety of Chinese Herbal Decoction Pieces Combined With Granules in the Treatment of Essential Hypertension Based on Chinese Herbal Formulas[J]. journal1, 2023, 43(1): 109-112.

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http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2023.01.044 OR http://www.hrbyybjb.org.cn/EN/Y2023/V43/I1/109

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