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Observation on the Preventive Effect of Vitamin A and C Combined With Ferrous Succinate and Folic Acid Tablets on Preeclampsia |
Pan Yuping, Cheng Jinhua, Fang Qiuxiang, Jin Bo |
Nanyang Second People's Hospital,Obstetrics and Gynecology,Nanyang 473000,China |
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Abstract Objective To explore the preventive effect of vitamin A and C combined with ferrous succinate and folic acid tablets on preeclampsia. Methods 152 pregnant women with high risk of preeclampsia from October 2016 to October 2019 in our hospital were selected as the research objects.According to the random number table,they were divided into observation group and control group with 76 cases each.Both groups of parturients received routine perinatal examination and health care.The control group received placebo treatment on the basis of routine care,and the observation group received vitamin A and C combined with ferrous succinate and folic acid tablets on the basis of routine care.The differences in blood pressure(SBP,DBP),placental hemodynamic indexes(PI,RI,S/D),preeclampsia incidence,and maternal and infant outcomes between the two groups of pregnant women before and after treatment were compared. Results After treatment,the levels of SBP,DBP,PI,RI,and S/D of pregnant women in the two groups were significantly lower than before treatment(P<0.05),and the observation group was significantly lower than the control group during the same period(P<0.05).The incidence of preeclampsia,placental abruption,and neonatal asphyxia in the observation group was significantly lower than that of the control group(P<0.05),and the Apgar score of newborns was significantly higher than that of the control group(P<0.05). Conclusion Vitamin A and C combined with succinate folic acid tablets can improve pregnant women's blood pressure and placental hemodynamics,effectively prevent the occurrence of preeclampsia,and contribute to good maternal and infant outcomes.
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Received: 16 September 2020
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