早期微量喂养支持治疗对极低出生体重儿肠道功能及生长发育的影响

doi:10.3969/j.issn.1001-8131.2023.02.007

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Abstract Objective To explore the effect of early micro-feeding support therapy on intestinal function and growth of very low birth weight infants. Methods 96 cases of very low birth weight newborns were randomly divided into treatment group and routine group,with 48 cases in each group.Among them,the newborns in the treatment group were given early micro-feeding,while those in the routine group were given routine feeding.The intestinal function [gastrointestinal motility（red stool discharge time）,complete meconium discharge time and abdominal distension relief time] of the two groups were compared.The levels of intestinal flora（lactobacillus,bifidobacteria）and GAStrointestinal hormones [gastrin（gas）,motilin（MTL）] were compared between the two groups before and after 7 days of treatment.The growth and development of newborns（recovery time of birth weight,growth rate of head circumference and growth rate of body length）were compared between the two groups. Results The time of complete discharge of red feces and meconium,the time of relieving abdominal distension and recovering birth weight in the treatment group were shorter than those in the routine group,and the difference was statistically significant（P<0.05）.The levels of Lactobacillus,Bifidobacterium and gastrointestinal hormone in the two groups of very low birth weight infants after 7 days of treatment were all higher than those before treatment,and the difference was statistically significant（P<0.05）,and the treatment group was higher than the routine group at the same time,and the difference was statistically significant（P<0.05）.The growth rate of head circumference and body length in treatment group was faster than that in routine group,and the difference was statistically significant（P<0.05）.Conclusion Early micro-feeding support therapy can promote the secretion of gastrointestinal hormones,regulate the balance of intestinal flora,improve the intestinal function and promote the growth and development of children.

Key words： Early micro-feeding support Very low birth weight infants Intestinal function growing development

Received: 09 February 2022

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R722

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	Chang Yuling

Cite this article:

Chang Yuling. Effect of early micro-feeding support therapy on intestinal function and growth of very low birth weight infants[J]. journal1, 2023, 43(2): 19-21.

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http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2023.02.007 OR http://www.hrbyybjb.org.cn/EN/Y2023/V43/I2/19

[1] 夏旭花,林露,华子瑜.氟康唑预防极低出生体重儿侵袭性真菌感染疗效和安全性的Meta分析[J].中国当代儿科杂志,2020,22(5):446-453.
[2] 张芸,刘玲.新生儿胃肠外营养脂肪乳剂的合理使用[J].中华实用儿科临床杂志,2020,35(14):1059-1063.
[3] 赵美林,郭华贤,袁二伟,等.早期微量喂养联合静脉营养与胃肠营养在早产低出生体重儿中的应用效果比较[J].中国食物与营养,2018,24(6):57-60.
[4] 王柱,高薇薇,沈阳,等.无创高频振荡通气在极低出生体重儿呼吸窘迫综合征拔管撤机后的应用[J].广东医学,2019,40(10):1391-1395.
[5] 熊小云,孙盼盼,庄燕珠,等.早期母乳喂养量对极低出生体重新生儿坏死性小肠结肠炎和喂养不耐受的影响[J].中华围产医学杂志,2020,23(3):6.
[6] 李玥,杨晓玲,马亮,等.GLP-1受体激动剂联合益生菌对糖尿病患者肠道菌群,氧化应激和糖脂代谢的影响[J].河北医药,2021,43(4):5.
[7] 井晓磊,张勇勤,顾亚娇,等.吴茱萸槟榔汤加减穴位贴敷治疗慢性非萎缩性胃炎的临床观察[J].中国实验方剂学杂志,2019,25(12):104-109.
[8] 唐丽明,宋宁,熊鹰,等.旋覆代赭汤加味治疗肝胃不和型难治性胃食管反流病的临床疗效及对胃肠激素的影响[J].辽宁中医杂志,2020,47(11):109-112.
[9] 杨璐颖,阮晓宇,王灵芝.益生菌联合早期微量喂养对早产儿肠道菌群及免疫功能影响的相关性研究[J].中国微生态学杂志,2019,31(6):694-698.
[10] 周学锋,童露云.布拉酵母菌散联合早期微量喂养对早产儿喂养不耐受及肠道菌群的影响[J].中国微生态学杂志,2019,31(8):919-922.
[11] 杨成香. 深耕母婴领域的研究,提供人体来源益生菌专访日本森永乳业株式会社基础研究所所长肖金忠博士[J].食品工业科技,2019,40(012):7-8.
[12] 向美芹,赵希平,李玮桐,等.初乳口腔护理对极/超低出生体重儿建立全肠道喂养过程的影响[J].中国实用护理杂志,2020,36(26):2039-2043.
[13] 王雪芹,何婧,何敏,等.父母参与发展性照顾联合袋鼠式干预对极低出生体重儿生长发育,神经行为及胃饥饿素水平的影响[J].中国儿童保健杂志,2021,29(3):5.
[14] 周结儿,吴鹏妹,韦婷艳.早期不同喂养方式对危重新生儿胃肠功能的影响[J].河北医药,2017,39(19):2998-2999,3002.
[15] 朱小冰,胡小苏,邹丹,等.早期母乳及母乳强化剂喂养对极低出生体重儿生长发育和营养状态的影响[J].中国儿童保健杂志,2021,29(10):4.