|
|
|
| The Effect of GnRH-combined Therapy in Patients with Adenomyosis on Indicators Related to Serum Recurrence |
| Wang Siyu |
| Third People's Hospital,Zhengzhou,Henan Province,450000 |
|
|
|
|
Abstract The target of adenomyosis and the combination of GnRH-（gonadotropin-releasing hormone agonist）and Manchester therapy. Methods 60 adenomyoses were selected,namely control group（n=30）and observation group（n=30）.Choose the former;on the basis,add GnRH-treat the latter and analyze different methods. Results After treatment,the uterine size,menstrual visual simulation score（VAS）and menstrual blood loss（PBAC）were significantly lower（P<0.05）,serum VEGF,MMP-2MMP-9（P<0.05）,and complication rate（P<0.05）. Conclusion For adenomyosis,the treatment effect of GnRH-a combined with Manchester,is significantly higher than that of Manchester,which can effectively reduce the uterine volume,reduce the level of inflammatory factors,and have the final effect of controlling recurrence factors,so as to promote the recovery of patients' condition faster.
|
|
Received: 07 March 2022
|
|
|
|
|
|
[1] 张盼盼,李萌,卢美松.子宫腺肌病合并不孕患者的生殖预后及助孕策略[J].国际妇产科学杂志,2019,46(1):23-26.
[2] 黄蓉,张娜,王佳丽,等.子宫腺肌症患者照护需求的质性研究[J].中国医学伦理学,2019,32(7):913-917.
[3] 徐锋,镡丽霞,李盼,等.高强度聚焦超声消融联合GnRHa治疗子宫腺肌病的临床研究[J].国际妇产科学杂志,2019,35(6):114.
[4] 齐进,邓晓红.GnRH-α联合LNG-IUS对子宫腺肌症患者血清CA125 VEGF FSH LH的影响[J].河北医学,2018,24(10):1615-1619.
[5] 谢幸,苟文丽.妇产科学.第8版,北京:人民卫生出版社,2013:274—276.
[6] 沈维维,虞晓潇.局限性子宫腺肌症病灶切除术后联合GNRH-a、曼月乐治疗的效果观察[J].浙江临床医学,2018,20(3):471-473.
[7] 张东雅,郭红军,邱海峰.GnRH-α联合曼月乐治疗子宫腺肌症患者的疗效及对血清复发相关指标的影响[J].实用医学杂志,2019(01):84-87.
[8] 王文莉,张颖,郭银树,等.GnRH-a 联合左炔诺孕酮宫内缓释系统治疗子宫腺肌病的临床疗效研究[J].医学综述,2018,24(13):2689-2692. |
| [1] |
Yang Yanping, WU Xianping, Feng Chaoqun, LI Xuelun, Chen Shihong. Effects of Remazolam on Serum IL-6,CRP and Postoperative Cognitive Function in Elderly Patients with Painless Gastroenteroscopy[J]. journal1, 2023, 43(3): 15-17. |
| [2] |
. [J]. journal1, 2023, 43(3): 73-75. |
| [3] |
Zhao Li. Efficacy of Doxthelline Combined with Methyl Johnson in COPD Patients with Acute Exacerbation and Its Effect on Serum Inflammatory Factor Levels[J]. journal1, 2023, 43(2): 5-7. |
| [4] |
Li Chunli. Effects of Hemodialysis on Inflammatory Factors and Renal Function in Diabetic Renal Failure[J]. journal1, 2022, 42(6): 15-16. |
| [5] |
. [J]. journal1, 2022, 42(6): 121-122. |
| [6] |
. [J]. journal1, 2022, 42(5): 96-98. |
|
|
|
|
2023, Vol. 43 
