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| Effects of Modified Double-hole and Conventional Three-hole Laparoscopic Surgery on Stress Response in Patients with Appendicitis |
| Xu Jinli, Lin Yingqi |
| Putian Binhai Hospital,Putian Fujian 351254,China |
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Abstract Objective To explore the effect of modified double-hole and conventional three-hole laparoscopic surgery on stress response in patients with appendicitis.Methods 80 patients with appendicitis were randomly divided into two groups,each with 40 patients.The control group was treated with conventional three-hole laparoscopic appendectomy（LA）,while the observation group was treated with modified double-hole LA.Operation-related indexes,stress response（norepinephrine（NE）,cortisol（Cor）,malondialdehyde（MDA）,superoxide dismutase（SOD）and complications were compared between the two groups.Results The amount of intraoperative bleeding in the observation group was less than that in the control group,and the operation time,the first anal exhaust and hospital stay were shorter（P<0.05）.On the first day after operation,Cor,NE and MDA in the two groups were higher than that before operation,but the observation group was lower than that in the control group.The SOD in the two groups was lower than that before operation,but the observation group was higher than that in the control group（P<0.05）.The incidence of complications in the observation group was lower than that in the control group（P<0.05）.Conclusion Compared with conventional three-hole LA,modified double-hole LA has less bleeding during operation,shorter operation time,can reduce the stress reaction of patients with appendicitis,and has fewer complications,which is beneficial to the rehabilitation of patients.
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Received: 20 February 2023
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2023, Vol. 43 
