慢性心衰患者经注射用环磷腺苷葡胺联合贝那普利治疗后心功能及血清炎性因子水平分析

doi:10.3969/j.issn.1001-8131.2023.03.003

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Abstract Objective To investigate the effects of injection of MCA combined with Benazepril（BNPH）on cardiac function and serum inflammatory factors in patients with chronic heart failure（CHF）.Methods 118 patients with CHFwere retrospectively collected and divided into 2 groups according to different treatment methods,with 59 cases in each group.Group B received benazepril and group A received INJECTION MCA combined with BNPH.Total response rate,left ventricular end diastolic diameter（LVEDD）,left ventricular ejection fraction（LVEF）,left ventricular end systolic diameter（LVESD）,N-terminal brain natriuretic peptide precursor（NT-probNP）,inflammatory factors [interleukin-6（IL-6）,tumor necrosis factor -α（TNF-α）were compared between the two groups before treatment and 14 days after treatment）.Results The total effective rate of group A was 93.22%（55/59）higher than that of group B（77.97%（46/59）（P<0.05）.LVESD and LVEDD in 14dA group were lower than those in B group,and LVEF was higher than those in B group（P<0.05）.The level of NT-probNP in 14dA group was lower than that in B group（P<0.05）.The levels of il-6 and TNF-α in 14dA group were lower than those in B group（P<0.05）.Conclusion Injection MCA combined with BNPH has obvious effect on CHF patients,which can effectively relieve inflammatory reaction,improve cardiac function and improve the condition.

Key words： chronic heart failure Benazepril Cardiac function Inflammatory factors Cyclophosphoadenosine meglumine for injection

Received: 06 July 2022

PACS:

R541.6+2

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	Gu Mengyao

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Gu Mengyao. Analysis of Cardiac Function and Serum Inflammatory Factors in Patients with Chronic Heart Failure Treated with AdP Combined with Benazepril[J]. journal1, 2023, 43(3): 7-9.

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http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2023.03.003 OR http://www.hrbyybjb.org.cn/EN/Y2023/V43/I3/7

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