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| Effect of CRRT on Nutrition and Micro Inflammation in Patients with Severe Infection |
| Ma Yan, Ding Yong, Wang Chenmeng |
| Department of critical medicine,General Hospital of Yima Coal Industry Group Co.,Ltd.,Yima 472300,China |
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Abstract Objective To investigate the effect of continuous renal replacement therapy（CRRT）on nutrition and micro inflammation in patients with severe infection. Methods 80 cases of severe infection patients were selected to carry out the study.The control group and the observation group were set up according to the complete regionalization method.The control group was given conventional hemodialysis,and the observation group was given CRRT treatment.The clinical related indicators,malnutrition status,body micro inflammation degree,inflammatory factor level and prognosis of the two groups were compared. Results There was no significant difference in HR,bun and Cr levels between the two groups before treatment（P>0.05）;After treatment,the levels of HR,bun and Cr in the two groups were significantly lower than those in the control group（P<0.05）;The total incidence of malnutrition in the observation group was 10.00%,which was lower than 30.00% in the control group（P<0.05）;CRP and TNF were detected before treatment in both groups-αThere was no significant difference in the levels of IL-6 and IL-6（P>0.05）;After treatment,CRP and TNF in the two groups were significantly higher than those in the control group-α.The levels of IL-6 and IL-6 in the observation group were lower than those in the control group（P<0.05）;The Apache Ⅱ score of the observation group was（16.65±2.95）points,which was lower than（24.27±4.12）points of the control group,the difference was statistically significant（P<0.05）,and the difference in the incidence of complications between the two groups was not statistically significant（P>0.05）. Conclusion CRRT in the treatment of patients with severe infection can obtain exact clinical effect,improve the malnutrition state of the body,alleviate the degree of micro inflammation,reduce the inflammatory reaction,and can present a good prognosis.
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Received: 08 July 2022
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2023, Vol. 43 
