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Quick Search     Adv Search 2016 Vol. 36, No. 4 Published: 2016-08-25 1 Bio-Transformation of Pregnenolone by Mucor Genevensis SUN Gongbing Microbial transformation of pregnenolone was studied in the Mucor genevensis culture, in which 7α,11α-dihydroxypregnenolone and 7α, 11 β- dihy droxypregnenolone were given from the metabolites. The biotransformation products were determined by IR，NMR and MS analysis. The results showed that the optimal condition for the biosynthesis of 7α ,11α—dihydr-roxy-pregnenolone was as follows: 3.5 %dextrose ,1.4% peptone , 0.16% potassium dihydydrogen phosphate, initial pH 4.5. The yield of 7α,11α-dihydroxypregnenolone was 59.2%. 2016 Vol. 36 (4): 1- [Abstract] ( 355 ) HTML (1 KB)  PDF  (0 KB)  ( 169 )

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