Abstract：Objective To investigate the clinical features and prognosis of 46 children patients with chronic renal failure（CRF）. Methods A retrospective analysis was performed on 46 children patients with CRF admitted to this hospital between May 2017 and April 2020.According to whether the prognosis was good,they were divided into the experimental group（23 cases,poor prognosis）and the control group（23 cases,good prognosis）.The clinical features and related influencing factors of prognosis were compared between the two groups of children patients with CRF. Results Among 46 children patients with CRF,there were 5 cases（10.87%）of unknown etiology and 41 cases（89.13%）of definite etiology.22 cases received symptomatic treatment（47.83%）,10 cases received renal transplantation（21.74%）and 14 cases received dialysis treatment（30.43%）.Common symptoms included 15 cases of vomiting（32.61%）,23 cases of edema（50.00%）,31 cases of anorexia（67.39%）and 30 cases of asthenia（65.22%）.The incidence rates of oliguria,edema,hyperkalemia,hyperchloremia,hyperphosphatemia,massive proteinuria and water-sodium retention of children patients with CRF in the experimental group were higher than those in the control group（P<0.05）.The application rate of renal transplantation was lower than that in the control group（P<0.05）.The dependent variable was whether the prognosis was good among children patients with CRF.Multivariate analysis found that hyperkalemia,hyperphosphatemia,massive proteinuria,water-sodium retention and renal transplantation were correlated with prognosis of children patients with CRF（P<0.05）. Conclusion Children patients with CRF will have a variety of clinical symptoms after the onset of the disease.The influencing factors of prognosis are hyperkalemia,hyperphosphatemia,massive proteinuria,water-sodium retention and renal transplantation.It is necessary to focus on the above factors to do symptomatic prevention and treatment in clinical practice.
郭楠. 46例慢性肾功能衰竭患儿的临床特点及预后分析[J]. 哈尔滨医药, 2021, 41(5): 31-33.
Guo Nan. Analysis of Clinical Features and Prognosis of 46 Children Patients With Chronic Renal Failure. journal1, 2021, 41(5): 31-33.
2021, Vol. 41 
