Abstract：Objective To explore the efficacy of vacuum-assisted excision（VAE）in the treatment of benign phyllodes tumors of breast（PTB）and related factors of local recurrence.Methods The clinical data of 116 patients with benign phyllodes tumors of breast were retrospectively analyzed,and the patients were grouped according to the surgical methods.The patients who underwent vacuum-assisted excision were selected as observation group（n=74）,and the patients undergoing routine local resection were set as control group（n=42）.The differences in surgical indicators（surgical time,incision length,intraoperative blood loss）and postoperative complications were compared between the two groups.The two groups of patients were followed up and the patients were divided into recurrence group（n=12）and non-recurrence group（n=104）according to whether the patients had local recurrence. Univariate analysis was performed on the data of patients.Multivariate Logistic regression analysis was performed on indexes with significant differences in univariate analysis.Results The surgical time,incision length and intraoperative blood loss in observation group were lower than those in control group（all P<0.05）.The incidence rate of local subcutaneous ecchymosis in observation group was lower than that in control group（P<0.05）,and there were no significant differences in the incidence rates of local hematoma,incision infection and recurrence between the two groups（all P>0.05）.Results of univariate analysis showed that the tumor size,a history of fibroadenoma and surgical margin in recurrence group were significantly different from those in non-recurrence group（all P<0.05）,and there were no significant differences in the age,menstrual status and surgical methods between the two groups（all P>0.05）.Multivariate Logistic analysis showed that tumor size ≥ 2.5 cm（OR=1.571,P<0.001）,a history of fibroadenoma（OR=1.740,P<0.05）and positive surgical margin（OR=1.394,P<0.05）were risk factors for recurrence in patients with benign PTB.Conclusion VAE has better efficacy in treating patients with benign PTB than conventional local resection.Tumor size,a history of fibroadenoma and surgical margin are related factors affecting local recurrence.
姚岚雅. 真空辅助旋切治疗乳腺良性叶状肿瘤的疗效及局部复发的相关因素分析[J]. 哈尔滨医药, 2022, 42(3): 12-14.
Yao Lanya. Efficacy of Vacuum-Assisted Excision on Benign Phyllodes Tumors of Breast and Analysis of Related Factors of Local Recurrence. journal1, 2022, 42(3): 12-14.
2022, Vol. 42 
