Clinical Prognostic Study on Intermediary Thrombolytic Therapy for Acute Ischemic Stroke Based on CTP
Zheng Jianghuan1, Wu Bangwu2, Yang Yingjing1
1. The Second Affiliated Hospital of Guizhou Medical University, Qiandongnan 556000, China; 2. Liping County People’s Hospital, Qiandongnan Prefecture, Guizhou 557300, China;
Abstract：Objective To investigate the prognostic evaluation value of CTP technology in AIS patients undergoing interventional thrombectomy. Method Clinical data of 83 AIS patients undergoing MT surgery were collected for retrospective analysis.They were divided into a good prognosis group of 52 cases and a poor prognosis group of 31 cases according to the mRS score.According to the mCTA score, they were divided into a good collateral circulation group of 54 cases and a poor collateral circulation group of 29 cases.According to the NIHSS score, they were divided into a significantly improved nerve defect group of 48 cases and a no significant improvement nerve defect group of 35 cases.The CTP perfusion parameters of patients in different groups were compared one week after surgery. Result The CTP perfusion parameters CBF, CBV, and HIR values of patients with good prognosis were significantly higher than those of patients with poor prognosis（P< 0.05）; The CTP perfusion parameters CBF, CBV, and HIR values of patients with good collateral circulation were significantly higher than those of patients with poor collateral circulation（P< 0.05）; The CTP perfusion parameters CBF, CBV, and HIR values of patients with significantly improved neurological deficits were significantly higher than those of patients with no significant improvement in neurological deficits（P< 0.05）. Conclusion CTP technology can effectively evaluate the postoperative collateral circulation status, degree of neurological dysfunction, and overall prognosis of AIS patients undergoing MT surgery by measuring parameters such as infarct core volume and ischemic penumbra.It provides a scientific reference for clinical prediction of HT risk and the formulation of next step treatment plans.
2023, Vol. 43 
