分析地诺前列酮栓与缩宫素在足月引产中的应用效果及安全性

doi:10.3969/j.issn.1001-8131.2023.05.009

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摘要目的对比和分析在足月引产中应用地诺前列酮栓及缩宫素的效果及安全性。方法随机选取82例进行足月引产的孕产妇,选用随机数字表法,将孕产妇分为对照组和观察组,对照组（n=41）孕产妇应用缩宫素,观察组（n=41）孕产妇应用地诺前列酮栓,比较两组孕产妇引产效果、分娩方式、诱发临产时间、产后出血量及用药后不良反应,对比两组自然分娩孕产妇产程。结果观察组引产效果明显优于对照组,两组引产总有效率差异有统计学意义（P<0.05）。观察组阴道分娩率高于对照组,剖宫产率低于对照组,两组分娩方式差异有统计学意义（P<0.05）。两组对比,观察组诱发临产时间更短,产后出血量更少,两组差异有统计学意义（P<0.05）。观察组第一产程、第二产程及总产程均短于对照组（P<0.05）,两组第三产程差异无统计学意义（P>0.05）。两组孕产妇用药后不良反应总发生率差异无统计学意义（P>0.05）。结论足月引产孕产妇应用地诺前列酮栓能够有效缩短诱发临产时间、提高自然分娩率、缩短产程,而且具有较高的用药安全性,值得临床应用。

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	苗艺璇

关键词 ：足月引产, 地诺前列酮栓, 缩宫素, 引产效果, 分娩方式, 安全性

Abstract：Objective To compare and analyze the effect and safety of dinoprostone suppository and oxytocin in term induced labor.Methods 82 pregnant and lying in women were randomLy selected.The pregnant and lying in women were divided into control group and observation group by random number table.The control group（n=41）was given oxytocin,and the observation group（n=41）was given dinoprostol suppository.The effect of labor induction,delivery mode,induced labor time,postpartum hemorrhage and adverse reactions of the two groups were compared,The birth process of the two groups of naturally delivered pregnant women was compared.Results The effect of induced labor in the observation group was significantly better than that in the control group,and the total effective rate of induced labor in the two groups was significantly different（P<0.05）.The vaginal delivery rate in the observation group was higher than that in the control group,and the cesarean section rate was lower than that in the control group.There was a statistically significant difference between the two groups in delivery methods（P<0.05）.Compared with the two groups,the time of induced labor in the observation group was shorter,and the amount of postpartum hemorrhage was less.The difference between the two groups was statistically significant（P<0.05）.The first stage of labor,the second stage of labor and the total stage of labor in the observation group were shorter than those in the control group（P<0.05）,and there was no significant difference in the third stage of labor between the two groups（P>0.05）.There was no significant difference in the total incidence of adverse reactions between the two groups（>0.05）.Conclusion Dinoprostone suppository can effectively shorten the induced labor time,improve the natural labor rate,shorten the labor process,and has high drug safety,which is worthy of clinical application.

Key words： term labor induction Dinoprostone suppository Oxytocin Effect of labor induction Mode of delivery Security

收稿日期: 2023-01-15

PACS:

R714.21

引用本文:

苗艺璇. 分析地诺前列酮栓与缩宫素在足月引产中的应用效果及安全性[J]. 哈尔滨医药, 2023, 43(5): 23-25.
Miao Yixuan. To Analyze the Effect and Safety of Dinoprostone Suppository and Oxytocin in Term Induced Labor. journal1, 2023, 43(5): 23-25.

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http://www.hrbyybjb.org.cn/CN/10.3969/j.issn.1001-8131.2023.05.009 或 http://www.hrbyybjb.org.cn/CN/Y2023/V43/I5/23

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