硫酸沙丁胺醇物与丙卡特罗物治疗支气管哮喘患儿的对比研究

doi:10.3969/j.issn.1001-8131.2024.01.011

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摘要目的对比分析硫酸沙丁胺醇与丙卡特罗治疗支气管哮喘（BA）患儿的研究效果。方法选取BA患儿90例,随机分为研究组（n=45）和常规组（n=45）,常规组予以丙卡特罗治疗,研究组予以硫酸沙丁胺醇治疗。比较2组临床疗效、肺功能[用力肺活量（FVC）、呼气流量峰值（PEF）、第1s用力呼气量（FEV1）]、哮喘症状评分、症状（哮鸣音、呼吸困难、咳嗽）消失时间及不良反应发生率。结果研究组总有效率95.56%（43/45）较常规组77.78%（35/45）高（P<0.05）;治疗后,研究组FVC、PEF、FEV1水平较常规组高（P<0.05）;治疗后,研究组哮喘日间症状、哮喘夜间症状评分均较常规组低（P<0.05）;研究组咳嗽、哮鸣音、呼吸困难消失天数均较常规组短（P<0.05）;2组不良反应发生率对比差异无统计学意义（P>0.05）。结论和丙卡特罗治疗相比,硫酸沙丁胺醇治疗BA患儿,可提高疗效,改善肺功能和临床症状,安全可靠。

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	白小航
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关键词 ：支气管哮喘, 硫酸沙丁胺醇, 丙卡特罗, 临床疗效, 肺功能

Abstract：Objective To compare and analyze the research effect of salbutamol sulfate and procaterol in the treatment of children with bronchial asthma. Methods 90 cases of children with bronchial asthma were selected and divided into an experimental group（n=45）and a control group（n=45）according to the random number table method.The control group was given procaterol drugs treatment,and the experimental group was was given salbutamol sulfate drugs treatment.The clinical efficacy,pulmonary function [forced vital capacity（FVC）,peak expiratory flow（PEF）,forced expiratory volume in the first second（FEV1）],asthma symptom score,symptom disappearance time（cough disappearance time,wheezing sound disappearance time,dyspnea disappearance time）and adverse reactions occurrence rate were compared between the two groups. Results The total effective rate of the experimental group 95.56%（43/45）was higher than that of the control group 77.78%（35/45）（P<0.05）;After treatment,the levels of FVC,PEF and FEV1 in the experimental group were respectively higher than those in the control group（P<0.05）;After treatment,the scores of asthma daytime symptoms and asthma nighttime symptoms in the experimental group were respectively lower than those in the control group（P<0.05）;The cough disappearance time,wheezing disappearance time and dyspnea disappearance time in the experimental group were respectively shorter than those in the control group（P<0.05）;There was no significant difference in the occurrence rate of adverse reactions between the two groups（P>0.05）. Conclusion Compared with the procaterol drugs treatment,salbutamol sulfate drugs treatment for children with the bronchial asthma can improve the curative effect,improve the pulmonary function and clinical symptoms.It is safe and reliable.

Key words： Bronchial asthma Salbutamol sulfate Procaterol Clinical efficacy Pulmonary function

收稿日期: 2023-02-20

PACS:

R562.2+5

引用本文:

白小航, 常振东, 穆艳艳. 硫酸沙丁胺醇物与丙卡特罗物治疗支气管哮喘患儿的对比研究[J]. 哈尔滨医药, 2024, 44(1): 35-38.
Bai Xiaohang, Chang Zhendong, Mu Yanyan. A Comparative Study of Salbutamol Sulfate and Procaterol in the Treatment of Children with Bronchial Asthma. journal1, 2024, 44(1): 35-38.

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http://www.hrbyybjb.org.cn/CN/10.3969/j.issn.1001-8131.2024.01.011 或 http://www.hrbyybjb.org.cn/CN/Y2024/V44/I1/35

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