Abstract:Objective To explore the clinical effect of pituitrin combined with carprost tromethamine in the prevention and treatment of postpartum hemorrhage. Methods A total of 102 women with high risk of postpartum hemorrhage were selected as subjects,and they were divided into study group and control group with 51 cases each according to the random number table method.The control group was treated with carboprost tromethamine,and the study group was treated with pituitrin on the basis of the control group.Observe the changes in the coagulation function(PT,APTT,PLT,Fbg)of the two groups immediately after delivery and 24h after delivery,and analyze and compare the differences in the amount of bleeding,the time to complete hemostasis,and the occurrence of adverse drug reactions within 24h after delivery. Results At 24h postpartum,the levels of PLT and Fbg of the two groups of parturients were significantly higher than those immediately after delivery,and the study group was significantly higher than the control group(P<0.05).Maternal PT and APTT levels in the two groups were significantly lower than those immediately after delivery,and the study group was significantly lower than the control group(P<0.05).The 30min,2h and 24h postpartum blood loss in the study group were significantly lower than those in the control group(P<0.05).The time taken by the mothers in the study group to completely stop bleeding was significantly lower than that in the control group(P<0.05).Within 24 hours after delivery,there was no significant difference in the incidence of nausea/vomiting,dizziness,and diarrhea between the two groups(P>0.05). Conclusion Pituitrin combined with carboprost tromethamine can effectively treat postpartum hemorrhage,improve the coagulation function of the parturient,and has good safety.
张艳萍, 王静. 垂体后叶素配合卡前列素氨丁三醇防治产后出血的临床效果探析[J]. 哈尔滨医药, 2021, 41(6): 38-40.
Zhang Yanping, Wang Jing. Analysis of the Clinical Effect of Pituitrin Combined With Carprost Tromethamine in Preventing and Treating Postpartum Hemorrhage. journal1, 2021, 41(6): 38-40.