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| Observation on efficacy of rectal administration of ibuprofen mixed solution on infantile febrile convulsion |
| Han Chuanying |
| Department of Pediatrics, Luohe Central Hospital,Luohe 462000,China |
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Abstract Objective To observe the efficacy of rectal administration of ibuprofen mixed solution on infantile febrile convulsion. Methods A total of 64 children patients with febrile convulsion were selected.All children patients were divided into control group and study group according to the random number table method,with 32 cases in each group.Control group were given ibuprofen and diazepam intramuscular injection on the basis of conventional treatment,and the study group were given ibuprofen mixed solution for rectal administration Control group was given conventional drugs and physical hypothermia,and study group was given rectal administration of ibuprofen mixed solution on the basis of control group.The treatment effects,and serum related indicators [neuron-specific enolase（NSE）and S-100β protein] were compared between the two groups,and the occurrence of adverse reactions,fever recurrence and convulsion recurrence were recorded in the two group. Results After treatment,the total effective rate in study group was higher than that in control group（93.75% vs 75.00%）（P<0.05）.After treatment,the levels of NSE and S-100β in the two groups were lower than those before treatment（P<0.05）,and the above-mentioned indexes in study group were lower than those in control group（P<0.05）.The total incidence rate of adverse reactions and recurrence rates of fever and convulsions in study group were lower than those in control group（P<0.05）. Conclusion For infantile febrile convulsion,rectal administration of ibuprofen mixed solution has significant treatment effects,reduce the serum NSE and S-100β protein,with low adverse reaction rate,but can also reduce the recurrence of fever and convulsions in children patients,with good clinical application value.
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Received: 06 February 2021
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[1] 许男,陈莹,刘蕊,等.我国小儿高热惊厥急救护理临床现状[J].中国急救复苏与灾害医学杂志,2017,12(5):480-483.
[2] 李娟,王丹,王艳,周高弦.小儿高热惊厥的危险因素及护理对策[J].实用临床医药杂志,2017,21(18):107-109.
[3] 李玉洁,侯静.地西泮对小儿高热惊厥复发的预防效果及对免疫功能的影响[J].中国妇幼保健,2018,33(8):1781-1784.
[4] 廖莉,文政.布洛芬不同给药途径治疗小儿发热的疗效观察[J].重庆医学,2012,41(36):3879-3880.
[5] 胡亚美,江载芳,诸福棠.实用儿科学[M].8版.北京:人民卫生出版社,2012.
[6] 吴亚臻,李琴.中西医结合治疗小儿高热惊厥的临床疗效[J].中国现代医学杂志,2018,28(16):83-87.
[7] 李清华. 急诊小儿高热惊厥的急救护理方法及效果评价[J].中国医疗设备,2017,32(S1):125-125.
[8] 刘兰花,郭银娟,张晓莹.小儿高热惊厥的影响因素及有效护理措施[J].海南医学,2018,29(16):147-149.
[9] 潘冬宁. 安定保留灌肠与静脉给药治疗小儿惊厥的比较分析[J].世界中医药,2017,12(S1):43-44.
[10] 宣文华. 布洛芬混合液联合地西泮直肠给药治疗小儿高热惊厥疗效观察[J].中国实用神经疾病杂志,2013,16(19):93-93. |
| [1] |
Wang Dongfang. Clinical Effect Observation of Esomeprazole in the Treatment of Peptic Ulcer[J]. journal1, 2022, 42(2): 11-13. |
| [2] |
Shao Jingtian, Huang Yan, Huang Lixian. Clinical Observation of Infection Index in Patients With Pulmonary Infection and Fever Treated With Doxycycline[J]. journal1, 2022, 42(2): 14-15. |
| [3] |
. [J]. journal1, 2022, 42(1): 59-60. |
| [4] |
. [J]. journal1, 2022, 42(1): 78-79. |
| [5] |
. [J]. journal1, 2022, 42(1): 87-87. |
| [6] |
. [J]. journal1, 2022, 42(1): 102-104. |
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2022, Vol. 42 
