89例薄层液基细胞学检查异常结果与组织病理学诊断结果的一致性对比分析

doi:10.3969/j.issn.1001-8131.2023.06.016

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Abstract Objective To explore the consistency between the abnormal results of thin-layer liquid-based cytology（TCT）and histopathological diagnosis in 89 cases. Methods The clinical data of 1113 female patients examined by TCT and histopathology were retrospectively analyzed, and the consistency between abnormal results of TCT and histopathological diagnosis was analyzed. Results Among the 89 cases of abnormal TCT, 40 cases were atypical squamous cells（ASC-US）, 8 cases were atypical squamous cells（ASC-H）with high epithelial lesions, 27 cases were low-grade squamous intraepithelial lesions（LSIL）, 13 cases were high-grade squamous intraepithelial lesions（HSIL）and 1 case was squamous cell carcinoma（SCC）.The coincidence rate between TCT diagnosis of SCC and pathological diagnosis was 100.00%.The diagnostic coincidence rate of TCT for HSIL was 76.92%, which was higher than that of LSIL（40.74%, P< 0.05）.The abnormal results of TCT showed that 41 cases（46.07%）were positive for LSIL and above, and 47 cases（52.81%）were positive for pathological diagnosis.There was no difference between them（P> 0.05）. Conclusion The abnormal results of TCT in 89 cases are consistent with the histopathological diagnosis, and TCT can be used as an effective supplementary method for the diagnosis of cervical lesions.

Key words： cervical cancer Cervical intraepithelial neoplasia Liquid thin layer cytology histopathology

Received: 12 December 2022

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R446.8

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	Articles by authors
	Wang Feigang
	Lu Junpeng
	Miao Hongyan

Cite this article:

Wang Feigang,Lu Junpeng,Miao Hongyan. Comparative Analysis of Consistency between Abnormal Results of Thin-layer Liquid-based Cytology and Histopathological Diagnosis in 89 cases[J]. journal1, 2023, 43(6): 44-46.

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http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2023.06.016 OR http://www.hrbyybjb.org.cn/EN/Y2023/V43/I6/44

[1] Kalliala I, Athanasiou A, Veroniki AA, et al.Incidence and mortality from cervical cancer and other malignancies after treatment of cervical intraepithelial neoplasia:a systematic review and meta-analysis of the literature[J].Ann Oncol.2020, 31(2):213-227.
[2] 杜祯, 陈锡山, 盛赠美.宫颈癌及宫颈上皮内瘤变患者宫颈液基薄层细胞学检查及高危型人乳头瘤病毒检测的临床价值[J].实用临床医药杂志, 2020, 24(17):24-27.
[3] 罗晶, 李婷婷, 王倩, 等.液基薄层细胞学检查, 人乳头状瘤病毒检测及阴道镜检查在宫颈癌前病变及宫颈癌筛查中的应用价值[J].新乡医学院学报, 2021, 38(5):427-430, 435.
[4] Zhu XH, Li XM, Zhang WL, et al.[Application of artificial intelligence-assisted diagnosis for cervical liquid-based thin-layer cytology][J].Zhonghua Bing Li Xue Za Zhi.2021, 50(4):333-338.
[5] 龙玉惠, 杨娇娥.人乳头瘤病毒DNA分型检测宫颈液基薄层细胞学检查及阴道镜活检组织病理学检查在宫颈癌筛查中的应用价值[J].中国妇幼保健, 2021, 36(10):2419-2421.
[6] Solomon D, Davey D, Kurman R, et al.The 2001 Bethesda System:terminology for reporting Results of cervical cytology[J].JAMA.2002, 287(16):2114-2119.
[7] Kurman RJ, Carcangiu ML, Herrington CS.WHO classification of tumours of female reproductive organs[M].Lyon:IARC, 2014.
[8] 苏丰丽, 孔为民.首都医科大学附属北京妇产医院近40年宫颈癌发病特点及趋势分析[J].中国计划生育和妇产科, 2021, 13(2):60-63.
[9] Brum VOR, Tricoti ASO, Pannain GD, et al.Cytology-based Screening for Anal Intraepithelial Neoplasia in Immunocompetent Brazilian Women with a History of High-Grade Cervical Intraepithelial Neoplasia or Cancer[J].Rev Bras Ginecol Obstet.2022, 44(7):678-685.
[10] Muthuswamy SK.Self-organization in cancer:Implications for histopathology, cancer cell biology, and metastasis[J].Cancer Cell.2021, 39(4):443-446.
[11] 邵桂芳, 王琛, 田红岩.阴道镜与病理学检测对宫颈癌前病变的一致性探究[J].中国性科学, 2019, 28(9):36-39.
[12] Beltrán-Guerrero LJ, García-Valdez R, Andrade-Amador V, et al.Comparación del Papanicolau con técnica convencional frente a técnica modificada[Comparison of the Pap smear with conventional technique versus modified technique][J].Rev Med Inst Mex Seguro Soc.2022, 60(2):164-170.
[13] 张露丹, 张建华, 张瑾, 等.对比传统巴氏涂片法与液基细胞学法在宫颈癌筛查中的作用[J].中国性科学, 2018, 27(12):34-36.
[14] Norimatsu Y, Yanoh K, Hirai Y, et al.A Diagnostic Approach to Endometrial Cytology by Means of Liquid-Based Preparations[J].Acta Cytol.2020, 64(3):195-207.
[15] Cao C, Yu X, Zhu T, et al.Diagnostic role of liquid-based cytology of bronchial lavage fluid in addition to bronchial brushing specimens in lung cancer[J].Tumori.2021, 107(4):325-328.
[16] 单继烈, 叶素梅, 王兰英, 等.液基薄层细胞学检测, 高危型人乳头状瘤病毒-DNA和人乳头状瘤病毒E6/E7 mRNA检测在宫颈癌早期筛查中的临床价值[J].中国卫生检验杂志, 2018, 28(6):667-669, 672.
[17] 陆亚玲, 张金玲, 许锬, 等.液基薄层细胞学, 高危型人乳头瘤病毒检查在宫颈癌及癌前病变筛查中的价值[J].中华疾病控制杂志, 2021, 25(10):1210-1213.
[18] 李玉梅, 黄伟, 唐喜军, 等.宫颈薄层液基细胞学异常妇女HPV检测及组织学随访结果分析[J].热带医学杂志, 2019, 19(7):840-843.
[19] 纪巧云, 邓巧玲, 郑朝晖.液基细胞学检查在宫颈癌筛查中的临床应用价值[J].中国妇幼保健, 2018, 33(7):1495-1498.