硫酸沙丁胺醇物与丙卡特罗物治疗支气管哮喘患儿的对比研究

doi:10.3969/j.issn.1001-8131.2024.01.011

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Abstract Objective To compare and analyze the research effect of salbutamol sulfate and procaterol in the treatment of children with bronchial asthma. Methods 90 cases of children with bronchial asthma were selected and divided into an experimental group（n=45）and a control group（n=45）according to the random number table method.The control group was given procaterol drugs treatment,and the experimental group was was given salbutamol sulfate drugs treatment.The clinical efficacy,pulmonary function [forced vital capacity（FVC）,peak expiratory flow（PEF）,forced expiratory volume in the first second（FEV1）],asthma symptom score,symptom disappearance time（cough disappearance time,wheezing sound disappearance time,dyspnea disappearance time）and adverse reactions occurrence rate were compared between the two groups. Results The total effective rate of the experimental group 95.56%（43/45）was higher than that of the control group 77.78%（35/45）（P<0.05）;After treatment,the levels of FVC,PEF and FEV1 in the experimental group were respectively higher than those in the control group（P<0.05）;After treatment,the scores of asthma daytime symptoms and asthma nighttime symptoms in the experimental group were respectively lower than those in the control group（P<0.05）;The cough disappearance time,wheezing disappearance time and dyspnea disappearance time in the experimental group were respectively shorter than those in the control group（P<0.05）;There was no significant difference in the occurrence rate of adverse reactions between the two groups（P>0.05）. Conclusion Compared with the procaterol drugs treatment,salbutamol sulfate drugs treatment for children with the bronchial asthma can improve the curative effect,improve the pulmonary function and clinical symptoms.It is safe and reliable.

Key words： Bronchial asthma Salbutamol sulfate Procaterol Clinical efficacy Pulmonary function

Received: 20 February 2023

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R562.2+5

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	Articles by authors
	Bai Xiaohang
	Chang Zhendong
	Mu Yanyan

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Bai Xiaohang,Chang Zhendong,Mu Yanyan. A Comparative Study of Salbutamol Sulfate and Procaterol in the Treatment of Children with Bronchial Asthma[J]. journal1, 2024, 44(1): 35-38.

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http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2024.01.011 OR http://www.hrbyybjb.org.cn/EN/Y2024/V44/I1/35

[1] 谢冰,张碧清,尹美祥.布地奈德辅助治疗小儿支气管哮喘对T淋巴细胞亚群及相关细胞因子的影响研究[J].临床合理用药杂志,2020,13(33):62-63.
[2] 兰小峰.胸腺肽联合沙美特罗替卡松对小儿支气管哮喘患者动脉血气及血清炎症因子的影响[J].慢性病学杂志,2020,21(10):1532-1533+1536.
[3] 马统帅,刘新光,单瑞娟,等.桃红四物汤加减联合GINA方案对小儿支气管哮喘的临床影响分析[J].中国合理用药探索,2020,17(11):78-81.
[4] 张婵,吕继忠.脾氨肽联合布地奈德雾化吸入治疗小儿支气管哮喘的效果及对免疫功能、炎性细胞因子的影响[J].齐齐哈尔医学院学报,2020,41(16):2009-2011.
[5] 胡文洁,郭燕军.布地奈德雾化吸入联合维生素A口服治疗小儿支气管哮喘的效果观察[J].临床医学,2020,40(11):93-94.
[6] 中华医学会儿科学分会呼吸学组,《中华儿科杂志》编辑委员会.儿童支气管哮喘诊断与防治指南(2016年版)[J].中华儿科杂志,2016,54(3):167-181.
[7] Qiu Wang,Weijian Zhang,Lilong Liu,et al.Effects of physical therapy on lung function in children with asthma:Study protocol for a systematic review and meta-analysis[J].Medicine(Baltimore),2019,98(15):e15226.
[8] 刘娟. 硫酸沙丁胺醇联合不同剂量布地奈德混悬液雾化吸入治疗小儿支气管哮喘合并肺炎支原体感染的临床观察[J].中国合理用药探索,2020,17(1):68-72.
[9] 俞琳,洪开听,占焕平,等.外周血血小板计数血小板分布宽度血小板平均体积及Th1/Th2细胞比值与支气管哮喘合并感染患儿病情变化的关系[J].中国妇幼保健,2022,37(1):65-67.
[10] 王艳琼,汤昱,陈超辉,等.葡萄糖酸锌联合硫酸镁、硫酸沙丁胺醇治疗小儿中-重度支气管哮喘的疗效观察及对炎性因子的影响[J].药品评价,2020,17(21):54-56.
[11] 程培培,周启立,任磊,等.支气管哮喘患儿血清25羟维生素D₃水平变化及补充维生素D治疗对患儿发病、预后的影响研究[J].临床和实验医学杂志,2021,20(3):323-326.
[12] 胡蓉,刘玉姣,肖洪洲,等.肺炎支原体感染诱发哮喘患儿外周血miR-33a与miR-222-3p及miR-492表达水平及意义[J].中华医院感染学杂志,2021,31(16):2517-2521.
[13] 朱静,孙志佳.盐酸左西替利嗪口服溶液联合丙酸氟替卡松气雾剂治疗过敏性鼻炎合并支气管哮喘患儿的临床研究[J].中国临床药理学杂志,2022,38(15):1727-1730.
[14] 张新利. 硫酸沙丁胺醇联合布地奈德雾化吸入治疗小儿支气管哮喘临床研究[J].世界复合医学,2020,6(11):166-168.
[15] 朱春红,王淑梅,肖峥峥,等.孟鲁司特钠联合盐酸丙卡特罗治疗儿童支气管哮喘的临床疗效分析[J].中国实用医药,2019,14(7):91-92.