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| Application Effect of Standard Large Trauma Craniotomy Combined with Sub-low Temperature in Severe Craniocerebral Trauma |
| Shen Jiangyi, Yang Ronggang, Liu Xu |
| Department of Neurosurgery of Nanshi Hospital,Nanyang 473000 Henan,China |
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Abstract Objective To analyze the effect of standard large trauma craniotomy combined with mild-hypothermia in severe craniocerebral trauma. Methods 76 cases of patients with severe craniocerebral trauma were selected,and they all were divided into an experimental group（n=38）and a control group（n=38）according to the method of random number table.The control group was treated with standard large trauma craniotomy,while the experimental group was treated with standard large trauma craniotomy combined with mild-hypothermia.The clinical efficacy,intracranial pressure level,national institute of health stroke scale（NIHSS）score,immune function（CD8+、CD4+）level and complicationsoccurrence rate of the two groups were compared. Results The total effective rate 94.74%（36/38）of the experimental groupwas higher than73.68%（28/38）of the control group（P<0.05）;After 1d,2d and 3d of treatment,the levels of intracranial pressure in the experimental group was lower than that in the control group（P<0.05）;After treatment,the NIHSS score of the experimental group was lower than that of the control group（P<0.05）;After treatment,the level of CD8+ in the experimental group was lower than that in the control group,while the level of CD4+ was higher than that in the control group（P<0.05）;The occurrence rate of complications 5.26%（2/38）in the experimental group waslower than 26.32%（10/38）in the control group（P<0.05）. Conclusion The standard large traumacraniotomy combined with mild-hypothermia in the treatment of severe craniocerebral trauma can improve the clinical efficacy,decrease the level of intracranial pressure,improve the state of neurological injury,improve the immune function and reduce the occurrence ofpostoperative complications.
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Received: 05 March 2023
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2024, Vol. 44 
