|
|
|
| Effect of Salvia Polyphenolic Injection on Angina Pectoris Attack and Cardiac Function Indexes in Patients With Stable Angina Pectoris |
| Wang Hewang |
| Department of General Internal Medicine,Zhumadian Cancer Hospital; Zhumadian 463000,China |
|
|
|
|
Abstract Objective To investigate the effect of salvianolate on cardiac function and safety in patients with stable angina pectoris. Methods 88 patients with stable angina pectoris were selected,and they were divided into two groups according to the random number table method,44 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with salvianolate.Angina pectoris attack,cardiac function,vascular endothelial function and adverse reactions were compared between the two groups. Results After treatment,the frequency of angina pectoris attack in the observation group was（1.06±0.21）times / week,which was less than that of the control group,and the attack time was（2.01±0.41）min,which was shorter than that of the control group（P<0.05）;after treatment,the left ventricular ejection fraction（LVEF）,cardiac output（CO）,E peak/A peak（E/A）of ventricular diastolic index in the observation group were（54.69±5.18）%,（5.08±0.89）L/min,（1.18±0.05）,which was higher than that of the control group（P<0.05）;After treatment,the nitric oxide（NO）of the observation group was（7.16±1.03）μmol/L,which was higher than that of the control group,and the endothelin-1（ET-1）was（53.62±5.24）ng/L,which was lower than that of the control group（P<0.05）;there was no serious adverse reaction in both groups. Conclusion Salvianolate can reduce the frequency of angina pectoris in patients with stable angina pectoris,shorten the duration,improve vascular endothelial function,and promote the recovery of cardiac function,which is safe and reliable.
|
|
Received: 06 October 2020
|
|
|
|
|
|
[1] 张亚静. 正胆汤加减治疗稳定型心绞痛的临床研究[J].现代中西医结合杂志,2017,26(1):42-44.
[2] 彭宾宾,韩颖,韩清华.麝香保心丸治疗稳定型心绞痛的疗效观察[J].中西医结合心脑血管病杂志,2017,15(4):460-462.
[3] 陈超,窦丽萍,陆明,等.丹红注射液治疗稳定型心绞痛(血瘀症)的临床研究[J].心脑血管病防治,2017,17(2):128-129.
[4] 中华医学会心血管病学分会,中华心血管病杂志编辑委员会.慢性稳定性心绞痛诊断与治疗指南[J].中华心血管病杂志,2007,35(3):195-206.
[5] 李秀珍,赵俊男,杨田田,等.养心氏片治疗冠心病稳定型心绞痛的临床疗效观察[J].中西医结合心脑血管病杂志,2017,15(2):133-136.
[6] 罗刚,叶穗林.黄连温胆汤加味治疗冠心病稳定型心绞痛患者疗效观察[J].中国中医急症,2017,26(3):520-522.
[7] 马云霞,马金莲.美托洛尔联合丹红注射液治疗稳定型心绞痛的疗效观察[J].宁夏医科大学学报,2019,41(4):404-407.
[8] 沈建中,田茂.大株红景天与单硝酸异山梨酯治疗稳定型心绞痛的疗效比较[J].中国循证心血管医学杂志,2018,10(10):1202-1204.
[9] 张洁函,庄少伟,鲁成,等.丹参酮ⅡA磺酸钠联合辛伐他汀治疗冠心病心绞痛的疗效及对血液流变学和血清TNF-α、CRP、ET-1、NO水平的影响[J].现代生物医学进展,2019,19(2):270-274. |
| [1] |
Zhang Guotao, Li Dongli, Wu Jing. Effect of Alteplase Thrombolysis Combined With Butylphthalide on Acute Cerebral Infarction[J]. journal1, 2021, 41(6): 1-3. |
| [2] |
. [J]. journal1, 2021, 41(6): 57-58. |
| [3] |
. [J]. journal1, 2021, 41(6): 138-139. |
| [4] |
Yuan Hui. Effects of Thrombolysis Time on Surgical Efficacy and Adverse Events in Patients With Acute ST-Segment Elevation Myocardial Infarction[J]. journal1, 2021, 41(5): 1-2. |
| [5] |
. [J]. journal1, 2021, 41(5): 93-94. |
| [6] |
Li Jingjing. Effect of Yiqi Tongmai Decoction on Cardiac Function and Inflammatory Response in Patients With Coronary Heart Disease and Heart Failure[J]. journal1, 2021, 41(4): 126-127. |
|
|
|
|
2021, Vol. 41 
