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| Effects of Thrombolysis Time on Surgical Efficacy and Adverse Events in Patients With Acute ST-Segment Elevation Myocardial Infarction |
| Yuan Hui |
| Department of Cardiovascular Medicine,Yongcheng People's Hospital,Shangqiu 576000,China |
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Abstract Objective To investigate the effects of thrombolysis time on surgical efficacy and adverse events in patients with acute ST-segment elevation myocardial infarction（STEMI）. Methods Using a retrospective research method,76 STEMI patients were set as the research subjects.After thrombolysis,both groups of patients were given coronary angiography to confirm the culprit vessels and performed percutaneous coronary intervention（PCI）.The patients were divided into two groups according to the different thrombolysis time.Patients with thrombolysis within 6 h of onset were selected as group A（n=40）,and patients with thrombolysis within 6h to 12h of onset were set as group B（n=36）.The left ventricular end-diastolic dimension（LVEDD）,left ventricular end-systolic dimension（LVESD）and left ventricular ejection fraction（LVEF）],vascular recanalization rate and incidence rate of major adverse cardiovascular events（MACE）were compared between the two groups after surgery. Results The LVEDD and LVESD of the two groups were decreased while the LVEF was increased.The recovery status of cardiac function of LVEDD [（53.22±4.88）mm VS（57.24±4.96）mm],LVEF [（40.13±4.05）mm VS（45.86±4.27）mm] and LVEF [（65.15±5.25）% VS（57.95±5.48）%] in group A were significantly better than those in group B（P<0.05）.Comparison of postoperative vascular recanalization rate between the two groups showed that the recanalization rate of group A was significantly higher than that of group B（87.5% VS 55.6%）（P<0.05）.The incidence rate of MACE of group A was lower than that of group B（5% VS 13.9%）（P>0.05）. Conclusion The earlier the thrombolysis time,the better the recovery of cardiac function in STEMI patients,the higher the vascular recanalization rate,and the lower the incidence of MACE.
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Received: 17 September 2020
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2021, Vol. 41 
