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| Analysis of the Clinical Effect of Pituitrin Combined With Carprost Tromethamine in Preventing and Treating Postpartum Hemorrhage |
| Zhang Yanping, Wang Jing |
| Department of Obstetrics,Zhengzhou Yihe Hospital,Zhengzhou 450000,China |
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Abstract Objective To explore the clinical effect of pituitrin combined with carprost tromethamine in the prevention and treatment of postpartum hemorrhage. Methods A total of 102 women with high risk of postpartum hemorrhage were selected as subjects,and they were divided into study group and control group with 51 cases each according to the random number table method.The control group was treated with carboprost tromethamine,and the study group was treated with pituitrin on the basis of the control group.Observe the changes in the coagulation function（PT,APTT,PLT,Fbg）of the two groups immediately after delivery and 24h after delivery,and analyze and compare the differences in the amount of bleeding,the time to complete hemostasis,and the occurrence of adverse drug reactions within 24h after delivery. Results At 24h postpartum,the levels of PLT and Fbg of the two groups of parturients were significantly higher than those immediately after delivery,and the study group was significantly higher than the control group（P<0.05）.Maternal PT and APTT levels in the two groups were significantly lower than those immediately after delivery,and the study group was significantly lower than the control group（P<0.05）.The 30min,2h and 24h postpartum blood loss in the study group were significantly lower than those in the control group（P<0.05）.The time taken by the mothers in the study group to completely stop bleeding was significantly lower than that in the control group（P<0.05）.Within 24 hours after delivery,there was no significant difference in the incidence of nausea/vomiting,dizziness,and diarrhea between the two groups（P>0.05）. Conclusion Pituitrin combined with carboprost tromethamine can effectively treat postpartum hemorrhage,improve the coagulation function of the parturient,and has good safety.
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Received: 22 October 2020
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[1] 陈敏,王心,尚丽新,等.产妇5272例产后出血发生情况分析[J].人民军医,2016,59(8):849-851.
[2] 陈洁,仇春波.卡前列素氨丁三醇对妊娠产后出血的临床研究[J].中国临床药理学杂志,2016,32(13):1182-1184.
[3] 琚绍静,刘伟,刘斌,等.垂体后叶素联合普萘洛尔治疗肝硬化并发上消化道出血的疗效观察和护理体会[J].安徽医药,2017,21(1):169-172.
[4] 刘兴会,杨慧霞.重视产后出血诊治过程的管理及评审[J].中华围产医学杂志,2016,19(4):252-253.
[5] 王瑞姣,韩汝芳,颜杰文,等.缩宫素联合卡前列素氨丁三醇预防高危产妇剖宫产产后出血的效果研究[J].中国妇幼保健,2016,31(15):3033-3035.
[6] 李微,王秀梅,邢梅.垂体后叶素配合卡前列素氨丁三醇治疗胎盘早剥产后大出血的临床疗效分析[J].河北医学,2016,22(2):221-223.
[7] 张淑敏. 凝血功能四项以及血小板检测在剖宫产产后出血中的临床价值[J].中国实验诊断学,2016,20(9):1564-1565.
[8] 江琴,刘正飞,黄佳蓉.垂体后叶素联合益母草注射液防治产后出血的效果及对氧化应激的影响[J].西北药学杂志,2019,34(6):798-802. |
| [1] |
Yang Ying, Xia Jinzhi, Lu Yongya. Application Value of Carprost Tromethamine in the Prevention of Hemorrhage After Cesarean Section[J]. journal1, 2021, 41(6): 35-37. |
| [2] |
. [J]. journal1, 2021, 41(6): 116-117. |
| [3] |
. [J]. journal1, 2021, 41(5): 77-77. |
| [4] |
Li Lina. Results of Coagulation Function Monitoring in Premature Infants of Different Gestational Ages and Their Correlation With Hemorrhagic Disease[J]. journal1, 2021, 41(4): 26-27. |
| [5] |
. [J]. journal1, 2021, 41(4): 72-73. |
| [6] |
. [J]. journal1, 2021, 41(2): 65-66. |
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2021, Vol. 41 
