阴道镜宫颈活检对宫颈癌前病变的诊断效能及漏诊因素分析

doi:10.3969/j.issn.1001-8131.2022.05.012

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (449 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study the diagnostic efficacy and analyze the missed diagnosis factors of colposcopy cervical biopsy in cervical precancerous lesions. Methods A total of 318 patients who were transferred for colposcopy due to abnormal cervical cancer screening were prospectively enrolled as subjects.Localized biopsies of 4 biopsy sites of the cervix were performed for each patient under colposcope（including targeted biopsy and random biopsy in the lesion or suspected lesion area）in order to evaluate the diagnostic efficacy of targeted and random biopsy for cervical precancerous lesions. Results Among the 318 patients,173（54.40%,173/318）were pathologically diagnosed with CIN II+,and 168（97.11%,166/173）were detected by colposcopy targeted biopsy with CIN II+.The sensitivity of colposcopy result with G2 as the threshold was lower than that with G1（71.43% and 97.11% respectively）.Randomized biopsy sites can increase the detection rate of targeted biopsies（P<0.05）.The detection rate of 1 biopsy site was lower than that of multiple biopsy sites（diagnostic sensitivity of 1,2,4 and 4 biopsy sites were 80.35%,97.69%,100.0%,100.0%,respectively）. Conclusion Colposcopy cervical biopsy has good diagnostic efficacy for cervical precancerous lesions.Incremental effect can be achieved through targeted biopsy and multiple biopsies during biopsy,and better diagnostic efficacy can be obtained by combining the results of cervical cancer screening and colposcopy diagnosis.

Key words： Colposcopy Cervical biopsy Cervical cytology examination High risk HPV test Pathological examination Precancerous lesions Diagnosis Analysis of missed diagnosis

Received: 19 July 2021

PACS:

R711.74

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Zhao Yanfang
	Hu Xingyun

Cite this article:

Zhao Yanfang,Hu Xingyun. Analysis of Diagnostic Efficacy and Missed Diagnosis Factors of Colposcopy Cervical Biopsy in Cervical Precancerous Lesions[J]. journal1, 2022, 42(5): 28-31.

URL:

http://www.hrbyybjb.org.cn/EN/10.3969/j.issn.1001-8131.2022.05.012 OR http://www.hrbyybjb.org.cn/EN/Y2022/V42/I5/28

[1] Li C.2019 ASCCP risk-based management consensus guidelines:methods for risk estimation,recommended management,and validation[J].Journal of Lower Genital Tract Disease,2020,24(2):90-101.
[2] 陈静,陈煜岊,弋文娟.阴道镜子宫颈活组织检查对子宫颈癌前病变诊断的准确性及子宫颈癌漏诊影响因素分析[J].肿瘤研究与临床,2020,32(8):579-583.
[3] 赵晓,张伟珍,王泽华,等.阴道镜下宫颈活检诊断宫颈上皮内瘤变的准确性及其漏诊宫颈癌的相关因素研究[J].中国妇幼保健,2020,35(10):1937-1940.
[4] 唐梦莹,尤志学.检出高级别子宫颈病变的阴道镜活检程序的优化[J].中华妇产科杂志,2021,56(3):192-199.
[5] 颛佳,张岱,贾芃,等.子宫颈四象限随机活检与阴道镜下定位活检HSIL+检出率比较[J].现代妇产科进展,2019,28(2):101-104,108.
[6] 唐梦莹,陈飞,尤志学.阴道镜下高级别子宫颈上皮内病变漏检的相关影响因素及防治对策[J].中华妇产科杂志,2020,55(12):876-880.
[7] 中国优生科学协会阴道镜和宫颈病理学分会(CSCCP)专家委员会.中国子宫颈癌筛查及异常管理相关问题专家共识(二)[J].中国妇产科临床杂志,2017,18(3):286-288.
[8] Zubair B.The bethesda system for reporting thyroid cytology(TBSRTC):from look-backs to look-ahead[J].Diagnostic Cytopathology,2020,48(10):862-866.
[9] Bornstein J.2011 colposcopic terminology of the International Federation for Cervical Pathology and Colposcopy.[J].Obstetrics and gynecology,2012,120(1):166-72.
[10] 王昀,马亚琪,刘爱军,等.WHO(2014)阴道、外阴肿瘤组织学分类[J].诊断病理学杂志,2014,21(12):787-788.
[11] Fan A.Diagnostic value of the 2011 International Federation for Cervical Pathology and Colposcopy Terminology in predicting cervical lesions[J].Oncotarget,2018,9(10):9166-9176.
[12] Khan M.ASCCP Colposcopy standards:role of colposcopy,benefits,potential harms,and terminology for colposcopic practice[J].Journal of Lower Genital Tract Disease,2017,21(4):223-229.
[13] 仓唯,洪祖蓓,顾李颖,等.转化区类型在评估阴道镜下未见宫颈病变者随机活检中的价值[J].上海交通大学学报(医学版),2020,40(9):1213-1217.